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NT - Emergency and critical care > blood products > Flashcards

blood products Flashcards

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Royal College: Emergency Medicine flashcards
1
Q

List 4 reasons that a blood transfusion might be given

A

Restore O2 carrying capacity
Restore blood volume
Provide blood components
Treat sepsis

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2
Q

Blood products

Whole blood

A

Fresh whole blood

Stored whole blood

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3
Q

Plasma

A

Fresh plasma

Frozen plasma

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4
Q

Platelet concentrate

A

not available in UK

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5
Q

Packed red blood cells - action

A

restore oxygen carrying capacity

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6
Q

Non-Labile clotting factors

A

(non fragile)

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7
Q

Non-Labile clotting factors

A

(non fragile)

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8
Q

Fresh whole blood - function

A

++ restores oxygen carrying capacity and blood volume ++

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9
Q

Fresh whole blood - constituents

A

RBCs, WBCs, platelets, plasma proteins, Calcium, fibrogen

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10
Q

Fresh whole blood -indications for use

A

haemorrhage, haemolysis, aplastic anaemia, thrombocytopaenia, coagulation disease, DIC. hypovolaemia

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11
Q

Fresh whole blood - shelf life

A

4 - 8 hours

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12
Q

Fresh whole blood - constituents

A

RBCs, WBCs, platelets, plasma proteins, Calcium, fibrogen

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13
Q

Fresh whole blood -indications for use

A

haemorrhage, haemolysis, aplastic anaemia, thrombocytopaenia, coagulation disease, DIC. hypovolaemia

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14
Q

Fresh whole blood - shelf life

A

4 - 8 hours

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15
Q

Fresh whole blood - storage

A

FRESH WHOLE BLOOD SHOULD NOT BE REFRIGERATED

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16
Q

Stored whole blood - function

A

restores oxygen carrying capacity and blood volume

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17
Q

stored whole blood - constituents

A

RBCs, WBCs, plasma proteins,

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18
Q

stored whole blood - indications for use

A

plasma replacement, haemolysis, anaemia, hypovolaemia, coagulopathy, DIC, bone marrow disease

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19
Q

stored whole blood - shelf life

A

coagulant - citrate phosphate dextorse - 21 days

coagulant - citrate phosphate dextrose adenine - 35 days

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20
Q

Stored whole blood - storage

A

1 - 6 C for 8 hours.
store upright
bags should be gently mixed by inversion several times a week

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21
Q

Packed red blood cells - constituents

A

PRBCs suspended in small volume of plasma and 100ml SAG-M

22
Q

Packed red blood cells - indications for use

A

Regenerative anaemia, non-regenerative anaemia, Acute blood loss, IMHA, Chronic blood loss- parasitism, bone marrow disorders

23
Q

Packed red blood cells - Shelf life

A

PRBC’s stored in SAG-M have a shelf life of 42 days

24
Q

Packed red blood cells - storage

A

1-6C

Store upright
space for air to circulate
bags mixed gently

25
Q

Fresh frozen Plasma (FFP) - product

A

plasma that has been seperated within 8 hours of collection

26
Q

Fresh frozen Plasma (FFP) - action

A

volume expansion, replace plasma factors, replace liable clotting factors

27
Q

Fresh frozen Plasma (FFP) - constituents

A

all plasma proteins (including labile CF)

28
Q

Fresh frozen Plasma (FFP) - indications for use

A

Coagulopathies, von Willebrands, loss of protiens, burns, GIT disorders, haemophillia A. DIC, pancreatitis, hypovolaemia.

29
Q

Fresh frozen Plasma (FFP) - shelf life

A

12 months

30
Q

Fresh frozen Plasma (FFP) - storage

A

-18C

31
Q

Frozen Plasma (FP) - product

A

plasma that has been separated from whole blood, >12 hours after collection but within the expiry date of the whole blood.

32
Q

Frozen Plasma (FP) - action

A

provides plasma factors and non liable clotting factors. Volume expansion

33
Q

Frozen Plasma (FP) - constituents

A

albuminm - non liable clotting factors

34
Q

Frozen Plasma (FP) - indications for use

A

deficiencies of non liable clotting factors.

35
Q

Frozen Plasma (FP) - shelf life

A

FP in CPD has a shelf life of 5 years

36
Q

Frozen Plasma (FP) - storage

A

-18C

37
Q

Platelet concentrate - Product

A

concentration of platelets

38
Q

Platelet concentrate - action

A

provides platelets

39
Q

Platelet concentrate - indications for use

A

thrombocytopaenia

40
Q

Platelet concentrate - shelf life

A

5 days

41
Q

Platelet concentrate - storage

A

22C

42
Q

Cryo - supernatant - constituents

A

non labile clotting factorsd, albumin and other plasma proteins

43
Q

Cryo - supernatant - indications of use

A

plasma protein deficients, hypovolaemia, coagulopathies

44
Q

Cryo - supernatant - shelf life

A

12 months

45
Q

Cryo - supernatant - storage

A

-18C

46
Q

Cryo - supernatant - storage

A

-18C

47
Q

Cryo - precipitate - action

A

restores labile clotting factors and plasma proteins

48
Q

Cryo - precipitate - constituents

A

20% fibrogren , 50% clotting factor VII

30% comprised of clotting factors

49
Q

Cryo - precipitate - indications for use

A

Inherited clotting factor deficiencies such as haemophillia A and VWD. Topical haemostatic in surgery.

50
Q

Cryo - precipitate - shelf life

A

12 months

51
Q

Cryo - precipitate - storage

A

-18C

NT - Emergency and critical care (3 decks)

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