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P&P 3 > Blood Products > Flashcards

Blood Products Flashcards

1
Q

what is the shelf life of PRBC?

A

42 days

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2
Q

1 unit of PRBC increases Hct by what?

A

3-4%

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3
Q

7 ml/kg will increase Hct by what?

A

10%

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4
Q

1 ml PRBC/kg will increase Hct by what?

A

1%

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5
Q

in a bleeding patient what do you want to keep the platelet count above?

A

50,000

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6
Q

one unit of platelets will increase platelet count by what?

A

10,000

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7
Q

what are apheresis platelets?

A

collected from a single donor

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8
Q

what is in 1 unit of FFP?

A

the plasma from 1 unit of whole blood

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9
Q

what are some indications for FFP?

A

single coagulation factor deficiency

warfarin effect

DIC

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10
Q

cryoprecipitate is valuable because it contains what?

A

fibrinogen

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11
Q

what fibrinogen levels require cryoprecipitate?

A

< 100 mg/dl

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12
Q

1 unit of cryoprecipitate will increase fibrinogen by what?

A

25 mg/100 ml

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13
Q

one unit of cryoprecipitate per 10 kg body weight raises fibrinogen by what?

A

50 mg/dl

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14
Q

what are the three types of complications from blood transfusions?

A

transfusion related complications

metabolic complications

infectious complications

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15
Q

what is acute hemolytic transfusion reaction (AHTR)?

A

when ABO incompatible blood is transfused, it results in RBC lysis and release of bradykinin and histamine

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16
Q

what are signs and symptoms of AHTR in an anesthetized patient?

A

fever
hypotension
hemoglobinurea

17
Q

what are signs and symptoms of AHTR in an awake patient?

A

fever
nausea
chest pain
flank pain

18
Q

how do you treat AHTR?

A

stop transfusion

send donor unit to blood bank

treat hypotension with fluids and vasopressors

monitor for DIC

19
Q

what is delayed hemolytic transfusion reaction?

A

extravascular hemolysis that occurs 2 days to months after transfusion

20
Q

what is the most common transfusion reaction?

A

febrile nonhemolytic transfusion reaction (FNHTR)

21
Q

FNHTR is most common with what blood product?

A

platelets

22
Q

what is TRALI?

A

severe pulmonary insufficiency following blood product transfusion

23
Q

what happens to potassium levels with transfusion?

A

hyperkalemia because PRBC storage causes leakage of potassium

24
Q

what happens to calcium levels with transfusion?

A

citrate binds to the calcium leading to hypocalcemia

25
Q

does the patient become acidotic or alkalotic after transfusion?

A

alkalosis is frequent because citrate is metabolized in the liver to bicarb

P&P 3 (6 decks)

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