Blood products Flashcards

1
Q

What does group A Rh- blood mean?

A

A-antigens on red cell membranes
Anti-B antibodies in plasma
Doesn’t have rhesus D antigen

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2
Q

What does group AB Rh+ blood mean?

A

A and B antigens on red cell membranes
No antibodies in plasma
Has rhesus D antigen

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3
Q

What blood can be given to anyone?

A

O Rh-

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4
Q

What does group O blood mean?

A

No antigens on red cell membranes

Anti-A and Anti-B antibodies in plasma

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5
Q

What blood products are there?

A
Whole blood
Platelets
Granulocytes
Fresh frozen plasma
Cryoprecipitate
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6
Q

What cryoprecipitate used for?

A

Source of fibrinogen
Factor VIII
vWF

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7
Q

What happens to blood to give someone red cells

A
Filtered
Anticoagulant added
Re-suspended in SAG-M
Stored at 2-6º
35 day shelf life
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8
Q

What happens to make a platelet sample?

A

Pooled from 4 donors or done by apheresis from single donor
Stored at room temperature
Constantly agitated

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9
Q

Where does fresh frozen plasma come from?

A
  • From men to avoid risk of transfusion reaction risk
  • Plasma from countries with low CJD risk for recipients born after 1996
  • Frozen at -25º and stored for 36 months
  • Used for clotting deficiencies
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10
Q

What can cause haemolysis when giving blood products?

A
Wrong A or B antigen
Rapid intravascular haemolysis
Inflammatory cytokines
Circulatory collapse and renal failure
Need ITU
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