Blood products Flashcards
What does group A Rh- blood mean?
A-antigens on red cell membranes
Anti-B antibodies in plasma
Doesn’t have rhesus D antigen
What does group AB Rh+ blood mean?
A and B antigens on red cell membranes
No antibodies in plasma
Has rhesus D antigen
What blood can be given to anyone?
O Rh-
What does group O blood mean?
No antigens on red cell membranes
Anti-A and Anti-B antibodies in plasma
What blood products are there?
Whole blood Platelets Granulocytes Fresh frozen plasma Cryoprecipitate
What cryoprecipitate used for?
Source of fibrinogen
Factor VIII
vWF
What happens to blood to give someone red cells
Filtered Anticoagulant added Re-suspended in SAG-M Stored at 2-6º 35 day shelf life
What happens to make a platelet sample?
Pooled from 4 donors or done by apheresis from single donor
Stored at room temperature
Constantly agitated
Where does fresh frozen plasma come from?
- From men to avoid risk of transfusion reaction risk
- Plasma from countries with low CJD risk for recipients born after 1996
- Frozen at -25º and stored for 36 months
- Used for clotting deficiencies
What can cause haemolysis when giving blood products?
Wrong A or B antigen Rapid intravascular haemolysis Inflammatory cytokines Circulatory collapse and renal failure Need ITU