Blood/lymph diseases Flashcards

1
Q

Hyper/hypotension

A

high/low blood pressure

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2
Q

Atherosclerosis

A

Clogged arteries

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3
Q

Thrombus

A

Clot that develops and persists in unbroken blood vessel (can lead to death)

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4
Q

Embolus

A

Freely floating thrombus

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5
Q

embolism

A

embolus obstructing blood vessel

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6
Q

Thrombocytopenia

A

deficient number of circulating platelets

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7
Q

Petechiae

A

Appear due to spontaneous, widespread hemorrhage from thrombocytopenia

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8
Q

Hemophilia

A

Hereditary bleeding disorders caused by missing factors (VIII, IX, XI)
A: most common type
B:
C: mild type

Prolonged bleeding. Treated by injecting missing factors

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9
Q

Disseminated Intravascular Coagulation

A

Clotting causes bleeding.

  • widespread clotting blocks intact blood vessels
  • severe bleeding occurs because residual blood unable to clot
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10
Q

Anemia

A

low O2 carrying capacity

*fatigue, shortness of breathe, pallor, chills

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11
Q

Blood Loss ANemias

A

Hemorrhagic – rapid blood loss (wound)
*replace blood

Chronic Hemorrhagic anemia – slight but persistaent blood loss
*primary problem treated

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12
Q

Low RBC production anemias

A

Irondeficiency anemia – low iron intakes
*iron supplements

Pernicious anemia – Autoimmune disease that causes stomach to destroy intrinsic factor producing mucosa
*B12 injections

Renal anemia – lack of EPO
-treated with synthetic EPO

Aplastic anemia – destruction of red marrow by dregs, chemicals, radiation, viruses

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13
Q

High RBC Destruction

A

Hemolytic anemias – Premature RBC lyssis

Thalassemias – one globin chain absent/faulty

Sickle-cell anemia – RBCs crescent shaped or rupture easily
*inhale nitric oxide, others

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14
Q

Polycythemia vera

A

Bone marrow cancer –> excessive RBCS

*severly increased blood viscosity

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15
Q

Secondary Polycythemia

A

Less O2 available (high altitudes) or EPO production increases. Blood doping

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16
Q

Leukopenia

A

Abnormally low WBC count

17
Q

Leukemias

A

Cancerous Leukocytes fill red bone marrow. Immature nonfunctional WBCs in bloodstream. Death from internal hemorrhage and infections

18
Q

Infectious Mononucleosis

A

Highly contagious. Like flu. “mono” high number of atypical agranulocytes

19
Q

Immunopathology

A

When immune cells interfere with normal cell physiology

20
Q

Type I : Immediate Hypersensitivity

A

(IgEAntibody mediated allergies. First time no symptoms; after many.
*Mast cells and Basophils. Histamine increased
IgE attach to mast cells and basophils after sensitivity stage. Next time antigens are identified and edema, mucous, vasodilation. Anaphylactic shock if systemic (bronchioles may collapse)

21
Q

Type II: Subacute Cytotoxic Hypersensity

A

IgM&G antibody response. Bind to antigens and cause complement and phagocytosis (wrong blood transfusion)

22
Q

Type III: Immune Complex Hypersensitivity

A

Insoluble antibodies that cannot be removed. Inflammation, cell lysis, and killing.

23
Q

Type IV: Delayed Type Hypersensitivity

A

Helper T Cells. (ex poison ivy). Cytokine activates macrophages and cytotoxic T cells

24
Q

Type V: Antibody Induced Cell Signaling Changes

A

Things meant to subdue actually stimulate

25
Q

Severe combined Immunodeficiency syndrom

A

Insufficient B and T cells. Treated with Bone marrow transplants

26
Q

AIDS

A

cripples immune system by destroying helper T cells

27
Q

pericarditis

A

Roughening of pericardial –> inflammation

28
Q

Angina Pectoris

A

Insufficeint blood supply to heart weakens cells

29
Q

Myocardial infarction

A

Death of cells due to lack of blood supply from blockage

30
Q

orthostatic hypotension

A

fainting upon standing because blood leaves head and pools in lower extremities