Blood Lecture #2 Flashcards
Define antigen
Anything that triggers an immune response
Define antibody
A group of plasma proteins that plays a role in immune response. Production of antibodies IS the immune response.
What are some of the functional roles of antibodies?
- Bind to an inactive virus (Neutralization)
- Antigen antibody complexes activate the complement system triggering its antibacterial activity
Define granulocyte
Immune cell (WBC) with granules containing enzymes.
Name all 3 granulocytes
- Neutrophils
- Eosinophils
- Basophils
Define agranulocyte
WBC without granules
Name all 2 agranulocytes
- Lymphocytes
- Monocytes
What is neutropenia?
Neutrophils levels that are lower than the reference range.
What would make children prone to neutropenia?
Bacterial Infections
What do you think granulocyte stimulating fracture stimulates?
Why would this mitigate the effects of neutropenia?
Hemopoietic stem cells.
It helps the bone marrow make more white blood cells
Why would a child (or adult) suffer from neutropenia?
Blood disorders, inadequate bone marrow production, cancer, infections, tuberculosis, hepatitis, sepsis, chemotherapy, etc.
A patient returning from a trop to Indonesia contracted a tape word from a contaminated drinking source. What cells would be elevated in response?
Eosinophils
A patient walks through poison ivy and had a severe allergic reaction with a skin rash. What cells would be elevated in response?
Basophils
You discover a new drug that works on white blood cells. To your amazement, you notice that this drug protects against bacterial infection by stimulating the WBC in question. What cells would this drug work on?
Neutrophils
During a viral infection with mono, what cells would you expect to be elevated?
Lymphocytes
