Blood Groups Flashcards
1
Q
Why is ABO the most important blood group?
A
People routinely have clinically significant ABO antibodies in their serum to the ABO antigens that they lack on their red cells
2
Q
A-group individuals have what antibodies in their serum?
A
B antibodies
3
Q
H antigen immunodominant sugar/gene product?
A
- a-2-fucosyltransferase
- fucose
4
Q
A antigen immunodominant sugar/gene product?
A
- a-3-N-acetylgalactosaminyltranferase
- N-acetylgalactosamine
5
Q
B antigen immunodominant sugar/gene product?
A
- a-3-D-galactosyltransferase
- galactose
6
Q
O antigen immunodominant sugar/gene product?
A
no gene product, only expresses H antigen
7
Q
ABO subgroup?
A
A1 - 80%
A2 - 20
differentate w anti-a1 lectin (dolichos biflorus)
8
Q
85-92% of red cell will react at IS…
A
will react with anti-D and be identified as D positive
