blood glucose concentration Flashcards
factors that influence blood glucose conc
diet
exercise levels
insulin
glucagon
adrenaline
glycogenisis
excess glucose converted to glycogen by liver
glycogenolysis
breakdown of glycogen back to glucose by liver
gluconeogenesis
glucose created form non-carbohydarte stores in liver e.g amino aicds and glycerol
when does gluconeogenesis occur
when glucose levels are low despite glycogenolysis occurring
when does inuslin action occur
insulin secreted when beta cells in isle of langerhans detect blood glucose levels are too high
insulin action
insulin attaches to receptors on target cells and changes the tertiary structure of the channel proteins so more glucose is absorbed into cells by facilitated diffusion
more protein carriers incorperated into membranes, even more glucose absorbed from blood into cells
glycogensis occurs, catalysed by activating enzymes
glucagon action when and where
glucagon produced by pancreas in response to low glucose levels
glucagon action
glucagon attaches to receptors on surface of target cells
stimulates adenylate cyclase to convert ATP into cAMP
cAMP acts as second messenger
activates enzyme protein kinase, hydrloyses glycogen to glucose
can also activate enzymes involved in gluconeogensis
what is a second messenger model
molecules inside a cell that transmit signals intracelluarly from the binding of an extracellular molecule to a receptor
adrenaline action
adrenaline attaches to receptors on surface of target cells
causes G protein to be acitvated and to convert ATP to cAMP
cAMP activates enxyme that hydrolyses glycogen to glucose
glycoenolysis occurs
occurs when blood gluc conc too low