Blood glucose and obesity Flashcards
What it glucose stored as and where is it stored?
- Glycogen
- the liver
What can consistently high blood glucose levels lead to?
blood vessel damage which causes:
- peripheral vascular disease
- cardiovascular disease
-stroke - microvascular disease ( damage to retina or kidney
- peripheral nerve dysfunction
Explain what happens when there is a rise in blood glucose levels?
- pancreas triggers secretion of insulin
- insulin travels to the liver where it binds to insulin receptors
- This causes glucose to be converted to glycogen
- This reduces blood glucose levels
Explain what happens when there is a drop in blood glucose levels?
- Pancreas increases the secretion of glucagon
- glucagon travels to the liver and catalyses the conversion of glycogen to glucose.
- blood glucose levels increase due to glucose being released by the liver
What is the relationship between insulin and glucagon?
antagonistic relationship - they have a negative feedback effect on each other
what hormone is produced in a fight or flight situation to increase blood glucose levels?
adrenaline
What is the difference in the cause of type 1 and type 2 diabetes
- type 1 diabetes is caused by pancreatic cells inability to produce insulin
- type 2 diabetes is caused by the insensitivity of the insulin receptors for the insulin.
What is the difference in the stages of life which type 1 and type 2 diabetes are diagnosed at?
- type 1 occurs in early childhood
- type 2 is usually later in life
difference in treatment between type 1 and type 2 diabetes?
- type 1 treated by regular insulin injections
- type 2 treated by regularly exercising, losing weight and controlling diet
What is obesity?
A condition characterised by accumulation of excess body fat in relation to lean tissue.
What is obesity a risk factor for?
cardiovascular disease and type 2 diabetes
how do you calculate a persons BMI?
weight(Kg)/ Height squared (metres)
What do different BMI ranges mean?
20-25= normal
26-30= overweight
31-40= obese
over 40 = morbidly obese
Why is BMI not always reliable?
People with a lot of muscle mass will be incorrectly classified as obese
How can obese people change their lifestyle to improve their health and weight?
- Reduce energy intake by limiting consumption of fat and free sugars
- regular exercise