Blood Gases Flashcards
pH
7.35 - 7.45
PO2
10 - 14 kPa
PCO2
4.5 - 6 kPa
Base excessive
-2 - 2 mmol/l
HCO3
22 - 26 mmol/l
1
Acidaemia or alkalaemia?
Look at pco2 and bicarb
If either abnormal may be mixed
Co2 changes
Resp
Bicarb changes
Metabolic
Resp alkalosis
Pneumothorax Asthma PE Hypervent Pneumonia Pulmonary oedema
Met alkalosis
Gi - vom/diarrhoea
Renal - Conn’s, Cushing’s, loop or thiazide diuretic, post hypercapnic
Hypokalaemia
Diuretics: h ion loss of contraction
Normal anion gap
8-16
Anion gap
Reflects unmeasured anions
Na-(hco3+cl)
High anion gap
Incr acid:
Exog: methanol, aspirin, ethylene glycol
Renal failure
Ketoacidosis: alcohol, starvation, diabetes
lactic acidosis: type a tissue hypoperfusion, b
Compensation
Ventilatory response: mins - hrs (resp)
Renal response: days (metabolic)
Chronic resp acidosis
High bicarb to concentrate
Acute resp acidosis
Bicarb normal can’t compensate quickly
Acute metabolic acidosis
Low CO2 to compensate
Metabolic alkalosis
Hypovent to compensate
CO2 incr
Simple acid base disorders
pH will be abnormal
Bicarb follows CO2
Resp acidosis
COPD,pneumonia, asthma, pulm oedema
Obstructive sleep apnoea,
Obesity, kyphosis, flail, scleroderma
Mnd
For every 1.3 incr in pco2 above 5.3
Hco3 incr by 3.5