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Haem > Blood film features > Flashcards

Blood film features Flashcards

1
Q

Acanthocytes

A

Spicules on RBCs due to unstable RBC membrane lipid

Splenectomy
Alcoholic liver disease
Spherocytosis

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2
Q

Anisocytosis

A

Variation in RBC size

Megaloblastic anaemia
Thalassaemia
IDA

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3
Q

Basophilic RBC stippling

A

Denatured RNA in RBCs showing defective Hb/EPO

Liver disease
Lead poisoning
Megaloblastic anaemia
Myelodysplasia
Hbopathy
Pyrimidine 5’ nucleotidase deficiency
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4
Q

Blasts

A

Myelofibrosis
Leukeamia
Malignant marrow infilitration

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5
Q

Cabot rings

A

Ring by membrane

Pernicious anaemia
Lead poisoning
Infections

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6
Q

Dimorphic picture

A

Mixed deficiency
Post-transfusion
1˚ sideroblastic

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7
Q

Howell-Jolly bodies

A

DNA nuclear remnants in RBCs normally removed by spleen

Hyposplenism
Dyserythropoietic states

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8
Q

Hypochromia

A

IDA
Thalassaemia
Sideroblastic

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9
Q

Left shift

A

Immature neuts released e.g. in infection

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10
Q

Leukoerythroblastic film

A

Immature cells ± tear drop RBCs

Haemolysis
Marrow infiltration/infection

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11
Q

Leukaemoid reaction

A

Leucocytosis seen in leukaemia/ infection/ burns

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12
Q

Pappenheimer bodies

A

Granules of siderocytes containing iron

Lead poisoning
Carcinomatosis
Post-splenectomy

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13
Q

Poikilocytosis

A

Variation in RBC shape

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14
Q

Polychromasia

A

RBCs stain differently depending on age

B12/folate deficiency
Haemolysis
Marrow infilitration

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15
Q

Reticulocytes

A

Suggests active erythropoiesis

Haemolysis
Haemorrhage
B12/iron/folate deficiency correction

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16
Q

Right shift

A

Hypermature white cells

Megaloblastic anaemia
Ureamia
Liver disease

17
Q

Rouleaux formation

A

Red cells stacking due to raised protein

Paraproteinaemia
Chronic inflammation
Myeloma

18
Q

Schistocytes

A

Fragmented RBCs sliced by fibrin bands in intravasc haemolysis

DIC
TTP
Pre-eclampsia

19
Q

Spherocytes

A

Hereditary spherocytosis

Autoimmune haemolytic anaemia

20
Q

Target cells

A

Liver disease
Hyposplenism
Thalassaemia
Few seen in IDA

21
Q

Tear-drop RBCs

A

Extramedullary haematopoiesis

Haem (10 decks)

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