Blood Film Flashcards

1
Q

reed-sternbeg cells

A

Hodgkins lymphoma

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2
Q

anisotcytosis

A

variation in size of RBCs

- high red cell distribution width

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3
Q

conditions anisocytosis seen in

A

myelodysplastic syndrome
haemolytic anaemia
iron deficient anaemia
post blood transfusion

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4
Q

auer rods

A

large, crystalline cytoplasmic inclusion bodies

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5
Q

auer rods conditions

A

acute myeloid leukaemia

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6
Q

basophilic stippling

A

presence of numerous basophilic granules that are disperse through the cytoplasm of RBCs in a peripheral smear

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7
Q

basophilic stippling conditions

A

lead poisoning
thalassaemia
sideroblastic anaemia
myelodysplasia

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8
Q

bite cells

A

RBCs tha contain a semi-circular indent on edge of membrane

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9
Q

Heinz bodies

A

individual bodies seen inside RBCs caused by denatured global

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10
Q

Heinz bodies conditions

A

G6PD deficiency

Alpha-thalassaemia

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11
Q

Howell-Jolly Bodies

A

individual bloods of RNA material seen inside RBCs

  • sign of spleen dysfunction
  • hyposplenism
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12
Q

Howell-Jolly bodies conditions

A

post-splenectomy

Severe anaemia

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13
Q

condition: hypo chronic RBC with central pallor

A

haemoglobinopathy (thalassaaemia)

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14
Q

reticulocytes

A

immature RBCs

  • larger
  • still contain RN
  • purple/blue
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15
Q

reticulocyte conditions

A

haemolytic naemia

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16
Q

Rouleux formation

A

stacks of aggregated RBCs

occur in increased plasma protein concentration

17
Q

rouleaux formation condition

A

myeloma
waldenstrom’s macroglobinaemia
inflammatory disorders
malignancy

18
Q

schistocytes

A

fragments of RBCs

19
Q

schistocyte conditions

A

HUS
DIC
thrombotic thrombocytopenic purport

20
Q

sideroblasts

A

immature RBCs containing blobs of iron

21
Q

sideroblasts conditions

A

myelodysplastic syndrome

22
Q

smudge cells

A

rupture WBCs

23
Q

Smudge cell conditions

A

chronic lymphocytic leukaemia

24
Q

spherocytes

A

spherical RBCs

25
Q

spheerocyte conditions

A

autoimmune haemolytic anaemia

hereditary spherocytosis

26
Q

target cells

A

pigmented central area surrounded by pale area then an outer ring of thicker cytoplasm
‘bulls eye’

27
Q

target cell conditions

A

iron deficiency anaemia

post splenectomy

28
Q

tear drop RBCs

A

poikolocytes

29
Q

teardrop RBCs conditions

A

myelofibrosis

severe iron deficiency

B-thalassaemia major §