Blood donation Flashcards
Registration and donor ID
Donors required to provide form of ID
Donor medical history
- History (and physical) must occur on day of donation
- Demographic info: name, DOB, address
- Most states allow donation at age 17
- Some states allow donation at age 16 with parental permission
- Donor must provide written consent
- Medical information
- Must be free of major diseases (heart, liver, lung), cancer, and have no abnormal bleeding tendency
- unless cleared by medical director
- Donor asked to report
- any illness developing within a few days after donation
- positive HIV or hepatitis result within 12 months after donation
- Must be free of major diseases (heart, liver, lung), cancer, and have no abnormal bleeding tendency
Indefinite donor deferrals
Indefinite
- Viral hepatitis after 11th birthday
- family history of CJD
- travelers who have spent >3 months in the UK or 5 years total in Europe due to risk of variant CJD
- Used a needle to administer nonprescription drugs
- Male who has had sex with another male since 1977
- Receipt of dura mater or pituitary growth hormone of human origin
- Confirmed positive test for HBsAg or repeatedly reactive test for anti HBc
- Lab evidence of HCV
- Lab evidence of HTLV-1
- Have donated the only unit of blood to a patient who developed HIV or HTLV and had no other probable cause of infection
- Use of bovine insulin manufactured in UK
- Etretinate (Tegison)
- History of babesiosis
- History of chagas disease
- stigmata of parenteral drug use or use of a needle to administer nonprescription drugs
- receiving money or drugs for sex
Allowable minimum blood donor intervals
- >= 16 weeks for 2 unit red cell donation by apheresis
- >= 8 weeks for single unit whole blood donation
- Plasmapheresis
- donor must weigh >= 110 lb (50 kg)
- “frequent” donor program: <= 2 donations/week, at least 2 days apart
- others: 4 weeks apart
Donor deferral for 3 years
Deferred for 3 years after last dose:
Acitretin (Soriatane)
Deferred for 3 years:
- Malarial infection (after becoming asymptomatic)
- lived for > 5 years in malaria endemic areas (after departure, if symptom free), regardless of prophylaxis
Donor deferral for 1 year
- paying for sex
- history of syphilis or gonorrhea, treatment for these infections, or positive syphilis screening test after completion of therapy
- Receipt of blood products, human tissue, or plasma derived clotting factors
- Hepatitis B immune globulin administration
- Any other unlisted vaccine
- Mucous membrane exposure to blood
- Nonsterile skin penetration, including tatoos or permanent makeup, unless applied by a state regulated entity with sterile needles and ink that has not been reused
- Residing with or having sexual contact with an individual with HIV or at high risk for HIV
- Incarceration for > 72 consecutive hours
- Travelers to malaria endemic areas after departure, if symptom free regardless of prophylaxis
Deferral period for person taking Dutasteride (avodart)
6 months after last dose
Blood donation physical exam
- Temperature measured orally <= 37.5 (99.5)
- Pulse: 50-100 (if athlete then can be less than 50)
- Blood pressure: no higher than 180 systolic and 100 diastolic
- Skin of venipuncture site must be free of lesions
- Hemoglobin and hematocrit must be >= 12.5 or 38% with blood taken at time of donation and cannot be obtained by earlobe puncture
Autologous donor requirements
- Physician order
- Hemoglobin >= 11 or hematocrit >=33%
- absence of any condition that places autologous donor at risk for bacteremia
- Blood must be collected > 72 hours prior to surgery
- unit can only be used autologously
Plasmapheresis volumes
- For automated instruments the allowable volume is predetermined by the FDA
- Manual separation procedures:
- no more than 500 ml of whole blood should be removed at one time unless the donor weighs >= 80 kg (175 lb); in this case as much as 600 ml can be removed at a time
Plateletpheresis
- interval for donation
- count required
- Interval <= 2/week, at least 2 days apart, <= 24 in 12 months
- If there is whole blood donation or if red cells cannot be returned to a donor during apheresis then 8 weeks must elapse before repeat apheresis
- Platelet count >= 150,000/ul
RBC apheresis and multicomponent donations
- if giving a single unit of RBCs with platelets and/or plasma, defered for 8 weeks
- if giving a double RBC donation by apheresis, deferred for 16 weeks
Blood obtained from therapeutic phlebotomy
- not used for allogeneic transfusion unless donor meets all requirements for allogeneic donation
- donors with MPN or hemoglobin synthesis disorders (e.g., PCT) are not acceptable donors
- Hemochromatosis
- if donor has no other medical conditions, the medical director may allow these units to cross over into blood supply; must be clearly labeled wtih donor condition
Information given to donor
- risks of phlebotomy
- infections transmitted by transfusion
- signs and symptoms of AIDS
- importance of giving accurate information
- importance of not donating if they have increased risk of infection
- reporting requirements of positive results to federal or state health authorities
What happens to units that donors request not be used?
These excluded units are still subjected to screening procedures