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Beau's Patho Comp Review 1 > Blood Disorders > Flashcards

Blood Disorders Flashcards

1
Q

Hemopoiesis

A

Production of RBCs

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2
Q

Erythropoietin

A

Made by kidneys

Regulate RBC production

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3
Q

Thrombopoietin

A

Made by the liver

Stimulates production of platelets

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4
Q

Plasmin

A

Breaks down blood clots

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5
Q

Epoetin Alfa

A

Artifical form of erythropoietin

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6
Q

Anemia

A

Reduction in oxygen transport

Less energy production in all cells

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7
Q

Anemia Symptoms

A 
Fatigue
Pallor
Dyspnea
Tachycardia (increased heart rate)
Peripheral vasoconstriction
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8
Q

Iron Deficiency Anemia

A

Insufficient iron impairs hemoglobin synthesis

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9
Q

Pernicious Anemia

A

Vitamin B12 deficiency
Characterized by very large immature RBCs
Will have less hemoglobin and shorter lifespans

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10
Q

Aplastic Anemia

A

Impairment or failure of bone marrow (drugs, viruses, autoimmune disorders)
Indicated by pancytopenia (decrease in all cells)

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11
Q

Hemolytic Anemia

A

Results from excessive destruction of RBCs

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12
Q

Sickle Cell Anemia

A

Abnormal hemoglobin

When deoxygenated, HbS is unstable and crystallizes

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13
Q

Thalassemia

A

Blood disorder involving less than normal amounts of hemoglobin

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14
Q

Polycythemia

A

Disease state in which proportion of blood volume that is occupied by red blood cells increases

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15
Q

Polycythemia Symptoms

A

Increased blood volume and viscosity can causes thrombosis and infarctions
Increased blood pressure
Hypertrophied heart

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16
Q

Disseminated Intravascular Coagulation

A

Excessive clotting and excessive bleeding in circulation

Thrombi and infarcts occur

17
Q

Leukemia

A

Group of neoplastic disorders involving WBCs

Uncontrollable production in bone marrow or lymph nodes

18
Q

Leukemia Symptoms

A

Frequent infection
Severe and steady bone pain
Weight loss and fatigue

19
Q

Acute Leukemia

A

High proportion of immature, nonfunctional cells (marked signs and complications)

20
Q

Chronic Leukemia

A

Higher proportion of mature cells (mild signs and better prognosis)

Beau's Patho Comp Review 1 (6 decks)

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