Blood Disorders

Question 1

In the morphological approach, anemia is classified by

Answer 1

the size of red blood cells

Question 2

The average size of an eythrochye is reflected in

Answer 2

the mean corpuscular volume (MCV)

Question 3

In clinical workup, the MCV will be

Answer 3

one of the first pieces of information available

Question 4

In mean corpuscular volume (MCV) what range is considered NORMOCYTIC?

Answer 4

80-110

Question 5

The _______ approach to anemia yields arguably the most clinically relevant classification of anemia

Answer 5

Kinetic

Question 6

Why might the kinetic approach be the most clinically relevant classification of anemia?

Answer 6

Because it compares erythrocyte production (reticulocyte count) vs destruction (Elevated LDH).

Question 7

Hemolytic Anemia is

Answer 7

Anemia involving increased destruction of Erythrocytes.

Question 8

Microcytic anemia is?

Answer 8

Anemia marked by small erythrocyte size, (average size count)

Question 9

Microcytic anemia is often the result of?

Answer 9

Iron Deficiency.

Question 10

Pure red cell aplasia (PRCA) is technically called

Answer 10

Erythroblastopenia

Question 11

Aplastic Anemia refers to

Answer 11

“inability to make mature blood cells of all types” anemia. -due to damaged

Question 12

Pernicious means

Answer 12

highly harmful, especially in a gradual or subtle way. In this context it really means that it was once a fatal condition.

Question 13

Pernicious anemia is of the __________ family.

Answer 13

megaloblastic (so macrocytic) family.

Question 14

The fundamental alteration of anemia is (definition)

Answer 14

a reduced oxygen-carrying capacity of the blood resulting in tissue hypoxia.

Question 15

Macrocytic anemias are also called _____________ anemias.

Answer 15

Megaloblastic.

Question 16

Macrocytic anemias are due to

Answer 16

B12 deficiency usually (leading to deficient erythrocyte DNA synthesis). The result is they die young, decreasing their circulating numbers, causing anemia.

Question 17

The most common type of anemia in the world is

Answer 17

Iron deficiency anemia.

Question 18

Koilonychia is

Answer 18

Spoon shaped fingernails. A sign of iron deficiency anemia.

Question 19

Sideroblastic Anemias are

Answer 19

a diverse group of anemias of varying severity. All due to inefficient iron uptake.

Question 20

Sideroblastic anemias can be;

Answer 20

Hereditary or reversable

Question 21

Phlebotomy is

Answer 21

The removal of blood from circulation.

Question 22

NORMOcytic, NORMOchromic anemias are characterizes by

Answer 22

y erythrocytes that are relatively normal in size and hemoglobin content but INSUFFICIENT IN NUMBER

Question 23

Clinical manifestations of anemia are:

Answer 23

Decreased oxygen delivery to tissues causes fatigue, dyspnea, syncope, angina, compensatory tachycardia, and organ dysfunction