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CLS > Blood Components > Flashcards

Blood Components Flashcards

1
Q

What 7 information is found on a blood component label?

A
  • Unique donor ID
  • Blood type (bar code)
  • Expiration
  • Special testing info
  • Collection facility (registration & license #)
  • Name of facility that modifies original product
  • Descriptive product code
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2
Q

An automated donation process that allows you to selectively donate only the blood components that are needed most, with the remaining blood being returned to you.

A

Apheresis

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3
Q

What is collected during an automated collection?

A

Power reds (2RBC), red blood cells, platelets and plasma

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4
Q

What are the ways to separate the components of blood from each other?

A

Centrifugation
Separation
Gravitational separation

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5
Q

What is the content of Whole Blood (WB)?

A

contains red cells, white cells, and platelets suspended in plasma

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6
Q

What an indication someone needs Whole Blood (WB)?

A

Symptomatic anemia with large volume deficit (trauma, surgery)

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7
Q

What is the storage period for all CPDA-1 blood components like WB and RBCs?

A

35 days

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8
Q

What is the storage period for ACD, CPD, CP2D Whole Blood (WB)?

A

21 days

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9
Q

What is the storage temperature for Whole Blood (WB)?

A

1-6C

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10
Q

What is the dosage for 1 WB in an adult (70kg)?

A

up hct 3% or hgb 1 g/dl

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11
Q

What are the contents of Red Blood Cells (RBC)?

A

Red cells

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12
Q

What is an indication someone needs RBC?

A

Symptomatic anemia, trauma, surgery

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13
Q

What is the storage period for ACD, CPD, CPD2 RBC?

A

21 days

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14
Q

What is the storage period for additive RBC?

A

42 days

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15
Q

What happens to RBCs if the seal is broken during processing?

A

RBCs must be transfused within 24 hours and new expiration date and time must be on the label and in the records

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16
Q

What is the storage temperature for RBCs?

A

1-6C

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17
Q

What is the dosage for RBCs for an adult (70kg)?

A

1 RBC, up hct 3% or hgb 1 g/dL

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18
Q

What is the content of Red Blood Cells, Leukocyte-Reduced (RBC-LR)?

A

Red cells, white cells reduced

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19
Q

What is the indication someone needs RBC-LR?

A

Symptomatic anemia, febrile reactions from leukocyte (WBC) antibodies

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20
Q

What is the storage period for CPDA-1 RBC-LR?

A

35 days

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21
Q

What is the storage period for additive RBC-LR?

A

42 days

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22
Q

What is the storage temperature for RBC-LR?

A

1-6C

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23
Q

What type of blood components are best for people with anemia?

A

Packed cells

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24
Q

What are the contents of Red Blood Cells, Frozen?

A

Deglycerolized red cells

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25
Q

What is the indication for RBCs, Frozen?

A

Symptomatic anemia

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26
Q

What is the freezer storage temperature and period of RBC, frozen?

A

-65C or below for 10 years

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27
Q

What is the thawed storage temperature and period for RBC, frozen?

A

1-6C for 24 hours

28
Q

What is the dosage for adult (70kg) for Red Blood Cells, Frozen?

A

1 RBC, up hct 3% or hgb 1g/dL

29
Q

What is the content of Fresh Frozen Plasma (FFP)?

A

Plasma prepared and frozen within 8 hours of WB phlebotomy & contains plasma proteins and all coagulation factors

30
Q

What is the indication for Fresh Frozen Plasma?

A

Deficient of labile and stable plasma coagulation factors

31
Q

What is the freezer storage temperature and period for Fresh Frozen Plasma?

A

-18C or below for 1 year

32
Q

What is the thawed storage temperature & period for Fresh Frozen Plasma?

A

1-6C for 24 hours

33
Q

What is the content of Frozen Plasma-24 hours (FP24)?

A

WB and apheresis plasma prepared and frozen within 24 hours of phlebotomy & contains plasma proteins and non-labile coagulation factors

34
Q

What is the content of Frozen Plasma-24 Hours (PF24RT24)?

A

Apheresis Plasma prepared within 24 hours after phlebotomy held at room temperature up to 24 hours after phlebotomy & plasma proteins and non-labile coagulation factors

35
Q

What is the indication of Frozen Plasma-24 Hours (FP24, PF24RT24)?

A

Deficient or defective plasma proteins and non-labile coagulation factors (so don’t give to a patient with coagulation issues)

36
Q

What is the freezer storage temperature and period for Frozen Plasma-24 hours?

A

-18C or below for 1 year

37
Q

What is the thawed storage temperature and period for Frozen Plasma-24 hours?

A

1-6C for 24 hours

38
Q

What is the content of Cryopreciptated Antihemophilic Factor (AHF, Cryo)?

A

Cold insoluble precipitate from thawed FFP & rich in Factor VIII, XIII, vWF, and Fibrinogen

39
Q

What is the indication for Cryoprecipitated Antihemophilic Factor?

A
  • Hemophilia A
  • von Willebrand’s Disease
  • Hypofibrinogenemia
  • Factor XIII deficiency
40
Q

What is the freezer storage temperature and period for Cryoprecipitated Antihemophilic Factor?

A

-18C or below for 1 year

41
Q

What is the thawed storage temperature and period for Cryoprecipitated Antihemophilic Factor?

A

RT for 6 hours or 4 hours if pooled

42
Q

What is the content of Plasma Cryoprecipitate Reduced?

A

Plasma residual from cryoprecipitate production and refrozen within 24 hours of thawing at -18C or below & deficient in fibrinogen, Factor VIII, Factor XIII, and von Willebrand Factor (vWF)

43
Q

What is the indication you should give Plasma Cryoprecipitate Reduced?

A

Provide clotting factors except fibrinogen, Factor VIII, Factor XIII, and von Willebrand Factor & plasma exchange for TTP

44
Q

What is the freezer storage temperature and period for Plasma Cryoprecipitate Reduced?

A

-18C of below for 1 year

45
Q

What is the thawed storage temperature and period for Plasma Cryoprecipitate Reduced?

A

1-6C for 5 days

46
Q

What is the content for Platelets (PLT, PLC, SDP, PP)?

A

Thrombocytes to help stop bleeding

47
Q

What is the indication you need platelets?

A

Low platelet count or platelet function abnormality

48
Q

What is the storage temperature and period of platelets?

A

20-24C for a period of 5 days with gentle agitation

49
Q

What is the dosage for platelets?

A

1 Platelet Concentrate (bag)/10 Kg body weight

50
Q

What is the adult dosage for platelets?

A

5-6 platelet concentrates (PLT, PLC) or 1

Single Donor Platelets (SDP, PP)

51
Q

What is the platelet concentrate?

A

1 Platelet Concentrate, up 5000-10,000/uL

52
Q

What is the platelet pheresis?

A

1 Platelet Pheresis, up 30,000-60,000/uL

53
Q

What is the content of granulocytes?

A

Concentrated leukocytes

54
Q

What is an indication you need granulocytes?

A

Neutropenia (low neutrophils) with infection

55
Q

What is the storage temperature and period for granulocytes?

A

20-24C; transfuse within 24 hours of collection

56
Q

What is the function of Irradiated Components (WB, RBC, Platelets)/

A

Stops proliferation of White Blood Cells and treats components with WBCs

57
Q

What is an indication someone needs Irradiated Components?

A

Prevents “graft vs host” disease in patients with immunodeficiency

58
Q

What is the storage period of Irradiated Components?

A

Expiration date is 28 days from irradiation, but not more than the original expiration date; irradiated platelets will retain the original expiration date since it is only a 5 day product

59
Q

What is the storage temperature of Irradiated Components?

A

Retains applicable component storage temperature

60
Q

What is Pathogen Reduction Technology (PRT)?

A

Treatment of platelets and plasma

61
Q

What is the function of Pathogen Reduction Technology (PRT)?

A

Reduces the infectious levels of pathogens

62
Q

What are the pathogens inactivated by PRT?

A

Viruses (CMV, Hep, HIV), bacteria (E. coli, pneumonia), parasites, WBC (inactivation of white cell replication; alternative to irradiation)

63
Q

What is Platelet Additive Solution (PAS)?

A

Crystalloid nutrient media

64
Q

What is the point of Platelet Additive Solution (PAS)?

A

Replaces a portion of plasma in platelet components and lowers risk for allergic transfusion reactions (potentially mitigates against TRALI)

65
Q

What tests are required for donor blood testing?

A

ABO (forward and reverse), DAT, IAT for Weak D, ABS, syphilis, Hepatitis, HIV, Chagas, ZIKA

66
Q

What tests are optional for donor blood testing?

A

Antigen screening (K, Fyb, E, etc), Hemoglobin S, Anti-CMV

CLS (6 decks)

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