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Blood Components Flashcards

1
Q

What 7 information is found on a blood component label?

A
  • Unique donor ID
  • Blood type (bar code)
  • Expiration
  • Special testing info
  • Collection facility (registration & license #)
  • Name of facility that modifies original product
  • Descriptive product code
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2
Q

An automated donation process that allows you to selectively donate only the blood components that are needed most, with the remaining blood being returned to you.

A

Apheresis

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3
Q

What is collected during an automated collection?

A

Power reds (2RBC), red blood cells, platelets and plasma

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4
Q

What are the ways to separate the components of blood from each other?

A

Centrifugation
Separation
Gravitational separation

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5
Q

What is the content of Whole Blood (WB)?

A

contains red cells, white cells, and platelets suspended in plasma

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6
Q

What an indication someone needs Whole Blood (WB)?

A

Symptomatic anemia with large volume deficit (trauma, surgery)

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7
Q

What is the storage period for all CPDA-1 blood components like WB and RBCs?

A

35 days

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8
Q

What is the storage period for ACD, CPD, CP2D Whole Blood (WB)?

A

21 days

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9
Q

What is the storage temperature for Whole Blood (WB)?

A

1-6C

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10
Q

What is the dosage for 1 WB in an adult (70kg)?

A

up hct 3% or hgb 1 g/dl

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11
Q

What are the contents of Red Blood Cells (RBC)?

A

Red cells

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12
Q

What is an indication someone needs RBC?

A

Symptomatic anemia, trauma, surgery

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13
Q

What is the storage period for ACD, CPD, CPD2 RBC?

A

21 days

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14
Q

What is the storage period for additive RBC?

A

42 days

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15
Q

What happens to RBCs if the seal is broken during processing?

A

RBCs must be transfused within 24 hours and new expiration date and time must be on the label and in the records

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16
Q

What is the storage temperature for RBCs?

A

1-6C

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17
Q

What is the dosage for RBCs for an adult (70kg)?

A

1 RBC, up hct 3% or hgb 1 g/dL

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18
Q

What is the content of Red Blood Cells, Leukocyte-Reduced (RBC-LR)?

A

Red cells, white cells reduced

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19
Q

What is the indication someone needs RBC-LR?

A

Symptomatic anemia, febrile reactions from leukocyte (WBC) antibodies

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20
Q

What is the storage period for CPDA-1 RBC-LR?

A

35 days

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21
Q

What is the storage period for additive RBC-LR?

A

42 days

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22
Q

What is the storage temperature for RBC-LR?

A

1-6C

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23
Q

What type of blood components are best for people with anemia?

A

Packed cells

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24
Q

What are the contents of Red Blood Cells, Frozen?

A

Deglycerolized red cells

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25
What is the indication for RBCs, Frozen?
Symptomatic anemia
26
What is the freezer storage temperature and period of RBC, frozen?
-65C or below for 10 years
27
What is the thawed storage temperature and period for RBC, frozen?
1-6C for 24 hours
28
What is the dosage for adult (70kg) for Red Blood Cells, Frozen?
1 RBC, up hct 3% or hgb 1g/dL
29
What is the content of Fresh Frozen Plasma (FFP)?
Plasma prepared and frozen within 8 hours of WB phlebotomy & contains plasma proteins and all coagulation factors
30
What is the indication for Fresh Frozen Plasma?
Deficient of labile and stable plasma coagulation factors
31
What is the freezer storage temperature and period for Fresh Frozen Plasma?
-18C or below for 1 year
32
What is the thawed storage temperature & period for Fresh Frozen Plasma?
1-6C for 24 hours
33
What is the content of Frozen Plasma-24 hours (FP24)?
WB and apheresis plasma prepared and frozen within 24 hours of phlebotomy & contains plasma proteins and non-labile coagulation factors
34
What is the content of Frozen Plasma-24 Hours (PF24RT24)?
Apheresis Plasma prepared within 24 hours after phlebotomy held at room temperature up to 24 hours after phlebotomy & plasma proteins and non-labile coagulation factors
35
What is the indication of Frozen Plasma-24 Hours (FP24, PF24RT24)?
Deficient or defective plasma proteins and non-labile coagulation factors (so don’t give to a patient with coagulation issues)
36
What is the freezer storage temperature and period for Frozen Plasma-24 hours?
-18C or below for 1 year
37
What is the thawed storage temperature and period for Frozen Plasma-24 hours?
1-6C for 24 hours
38
What is the content of Cryopreciptated Antihemophilic Factor (AHF, Cryo)?
Cold insoluble precipitate from thawed FFP & rich in Factor VIII, XIII, vWF, and Fibrinogen
39
What is the indication for Cryoprecipitated Antihemophilic Factor?
- Hemophilia A - von Willebrand’s Disease - Hypofibrinogenemia - Factor XIII deficiency
40
What is the freezer storage temperature and period for Cryoprecipitated Antihemophilic Factor?
-18C or below for 1 year
41
What is the thawed storage temperature and period for Cryoprecipitated Antihemophilic Factor?
RT for 6 hours or 4 hours if pooled
42
What is the content of Plasma Cryoprecipitate Reduced?
Plasma residual from cryoprecipitate production and refrozen within 24 hours of thawing at -18C or below & deficient in fibrinogen, Factor VIII, Factor XIII, and von Willebrand Factor (vWF)
43
What is the indication you should give Plasma Cryoprecipitate Reduced?
Provide clotting factors except fibrinogen, Factor VIII, Factor XIII, and von Willebrand Factor & plasma exchange for TTP
44
What is the freezer storage temperature and period for Plasma Cryoprecipitate Reduced?
-18C of below for 1 year
45
What is the thawed storage temperature and period for Plasma Cryoprecipitate Reduced?
1-6C for 5 days
46
What is the content for Platelets (PLT, PLC, SDP, PP)?
Thrombocytes to help stop bleeding
47
What is the indication you need platelets?
Low platelet count or platelet function abnormality
48
What is the storage temperature and period of platelets?
20-24C for a period of 5 days with gentle agitation
49
What is the dosage for platelets?
1 Platelet Concentrate (bag)/10 Kg body weight
50
What is the adult dosage for platelets?
5-6 platelet concentrates (PLT, PLC) or 1 | Single Donor Platelets (SDP, PP)
51
What is the platelet concentrate?
1 Platelet Concentrate, up 5000-10,000/uL
52
What is the platelet pheresis?
1 Platelet Pheresis, up 30,000-60,000/uL
53
What is the content of granulocytes?
Concentrated leukocytes
54
What is an indication you need granulocytes?
Neutropenia (low neutrophils) with infection
55
What is the storage temperature and period for granulocytes?
20-24C; transfuse within 24 hours of collection
56
What is the function of Irradiated Components (WB, RBC, Platelets)/
Stops proliferation of White Blood Cells and treats components with WBCs
57
What is an indication someone needs Irradiated Components?
Prevents "graft vs host" disease in patients with immunodeficiency
58
What is the storage period of Irradiated Components?
Expiration date is 28 days from irradiation, but not more than the original expiration date; irradiated platelets will retain the original expiration date since it is only a 5 day product
59
What is the storage temperature of Irradiated Components?
Retains applicable component storage temperature
60
What is Pathogen Reduction Technology (PRT)?
Treatment of platelets and plasma
61
What is the function of Pathogen Reduction Technology (PRT)?
Reduces the infectious levels of pathogens
62
What are the pathogens inactivated by PRT?
Viruses (CMV, Hep, HIV), bacteria (E. coli, pneumonia), parasites, WBC (inactivation of white cell replication; alternative to irradiation)
63
What is Platelet Additive Solution (PAS)?
Crystalloid nutrient media
64
What is the point of Platelet Additive Solution (PAS)?
Replaces a portion of plasma in platelet components and lowers risk for allergic transfusion reactions (potentially mitigates against TRALI)
65
What tests are required for donor blood testing?
ABO (forward and reverse), DAT, IAT for Weak D, ABS, syphilis, Hepatitis, HIV, Chagas, ZIKA
66
What tests are optional for donor blood testing?
Antigen screening (K, Fyb, E, etc), Hemoglobin S, Anti-CMV

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