Blood Clotting Disorders Flashcards
What kind of genetic link does Hemophilia have?
Sex link, its connected to the X chromosome
How many types of Hemophilia are there? What are they called?
3 - A, B and D
C sir! C!
What does DIC stand for?
Disseminated Intravascular Coagulation
True or False: Disseminated Intravascular Coagulation only has massive clotting with normal bleeding levels.
False: it has excessive bleeding AND excessive clotting
What about DIC depletes the body of clotting factors and platelets?
It over produces many small blood clots throughout the body
What condition is a big trigger to initiate DIC?
Pregnancy, many obstetric complications can spur it
MDS (Myelodysplastic Syndrome) refers to a class of disorders which include what issue?
Cells in the bones code themselves improperly causing inadequate production of cells by bone marrow
True of False: Aplastic Anemia and Deficiency Dyscrasias are both included with in the category of MDS?
True
AT what age does MDS start appearing?
over 50
A Bone marrow transplant is typically curative, what prevents it from happening?
The patients health will often not allow for it
What is MDS usually a precursor to?
Leukemia
What kind of cells do Leukemias affect?
White blood cells
What characterizes Acute Leukemia?
High proportion of immature, non-functional cells int eh bone marrow and peripheral circulation.
Does chronic Leukemia have a more favorable prognosis? Why?
Yes, it has a higher proportion of mature cells
What normally causes death in Leukemia?
Overwhelming infection or hemorrhage