Blood — Cell Anatomy + Functions Flashcards

1
Q

Blood

  • composition
  • m v f
  • % body weight
A
  • composed of LIQUID + SOLID parts
    &raquo_space;55% plasma vs 45% cells (RBC/WBC/platelets)
  • women have less than men. 5 vs 6 liters
  • 8% of body weight (Integ system 15%)
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2
Q

maids (9)

Functions of Blood

A
  • maintain homeostasis #maids
  • Nags = Speeds you up = Enzymes/RXNs
  • Food = Carries nutrients to cells
  • Cleans = takes away waste (CO2) interstitial fluid
  • Brings you calls = Transports hormones = communication b/n organs
  • Air Freshner = Maintains stable smell conditions = doesn’t allow pH to be <7.35 or >7.45
  • Brings you blankets = regulates your temp.
  • hydrates you = osmosis. regulates water content of cells through Na+ ions
  • heals you = clotting mechanism
  • protects you from strangers = or against foreign microorganisms + toxins
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3
Q

Erythrocytes

  • appearance
  • composition
  • characteristics
  • life span
  • functions
  • % in blood
A

– biconcave disks (like doughnut). no nucleus. Simple.

– protein network a.k.a. stroma. cytoplasm. Lipids: cholesterol, hemoglobin.

– hemoglobin one third of cell. do not divide because no nucleus.

– 120 days

– Combine with oxygen in lungs. Transport it to tissues. Combine with CO2. Transport it to lungs.

— 95% of cells in blood are RBCs

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4
Q

Hemoglobin

– what is it
– composition
– function + location
– appearance
– prevalence in gender + why
A

– pigment in RBC

– Globin = protein. Hemo = pigment.

– hemo: binds with oxygen (b/c of 4 iron molecules) / globin = binds with CO2

– O2 found in lungs. Transported to cell/tissues. CO2 found in interstitial fluid. Carried to lungs

– hemoglobin w/ oxygen: bright red ; hemoglobin w/o oxygen: dark red

– unit: # RBC (in millions) per mm3 / Men: 5.4 / Women: 4.8 (menstruation 👉🏼 need more iron)

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5
Q

Leukocytes

  • what are they
  • etymology + why
  • function
  • broad types
  • appearance + characteristic
  • main forms of attack
  • % in blood
A
  • cells found swimming in blood
  • Leuko=white. Because no pigment. But YES nucleus
  • immune system: combat inflammation + infection
  • Wright’s stain: granulosa/no granulosa
  • larger than WBC / can leave blood into tissues
  • ameboid movement -> phagocytosis
  • about 5%:
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6
Q

Ameboid movement

  • what is it
  • how it works
  • purpose
  • aided by? + definition
A
  • name given to WBC ability to move from blood to tissues
  • sends out cytoplasmic extension that attached to an object. Rest or cells contents then flows through that extension.
  • attack invading microorganismos. Clean up cellular debris
  • phagocytosis: eating up the microorganism or cell debris
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7
Q

Phagocytosis

  • what is it
  • etymology + why
A
  • process by which WBCs get rid of invading microorganismos and cellular debris
  • phago = eating, because that’s what they do to the above
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8
Q

Types of WBCs

  • granules -> NEBulosa
  • no granules -> ML (melissa lizbeth, no freckles)
A
  • Neutrophils (majority of WBCs in blood)
  • Eosinophils (minority)
  • Basophils (minority)
  • Monocytes (minority but huge)
  • Lymphocytes (majority but lesser)
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9
Q

Neutrophils

  • % in blood + behavior
  • habits
  • function + why
  • appearance to us + it’s composition
A
  • more than 60%. Very active in blood
  • stays in blood for about 12h. Moves into tissues then.
  • phagocytize stuff in tissues to get rid foreign stuff. Secrete lysosomes to destroy bad bacteria
  • pus: dead neutrophils. Fluid. Debris
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10
Q

Monocytes

  • what are they
  • characteristic
  • functions
  • %
A
  • HUGE WBCs found in blood
  • largest leukocytes in body. can leave blood and enter tissues
    &raquo_space; if found in tissues, new not monocytes but macrophages)
  • immune surveilance
  • phagocytosis of bacteria, dead cells or cell debris.
  • around 5%
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11
Q

Eosinophils

  • what are they + function
  • how?
  • %
A
  • WBC in charge of destroying allergens AND some parasites
    &raquo_space; allergens: stuff that produces you allergies like pollen/cat hair
  • produce anti-hisitamine
  • less than 5%
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12
Q

Basophils

  • what are they
  • function
  • how it achieves such + describe
  • % in blood
A
  • WBC that also involved in combatting allergic RXNs
  • inflammatory response
  • release heparin, histamine and serotonin TO tissues
    &raquo_space; heparin: anticoagulant
    &raquo_space; histamine: causes inflammation
    &raquo_space; serotonin: causes vessels to constrict
  • least present. 0.5% to 1%
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13
Q

Lymphocytes

  • what are they
  • characteristics
  • life span
  • appearance
  • types + main functions
  • overall functions (4)
  • %
A
  • WBCs in charge of producing antibodies
  • very important in immune response.
  • much less numerous in blood than RBCs.
  • can only phagocytize certain stuff lest they suffer metabolically.
  • life spain = short, only days. if infection, only hours
  • very tiny WBC. smallest of them all. excluding platelets
  • B lymphocytes: antibody production. precursos of plasma cells
  • T lymphocytes: cellular immune response
  • control cancer cells, destroy microorganisms, destroy parasites, reject foreign tissue implants
  • 20 to 25%
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14
Q

Thrombocytes

  • AKA?
  • what are they?
  • size
  • function
  • life spain
  • where produced and from what.
A
  • aka platelets
  • cellular fragments WITH nucleus
  • 2-4 um. HUGE cell to tiny cell fragments
  • prevent fluid loss when blood vessels break. part of blood clotting mechanism.
  • live for about a week
  • produced in RED bone marrow. derived from megakaryocytes.
    &raquo_space; one of 5 ways blood stem cell differentiates
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15
Q

Plasma

  • what is it + % in blood
  • components + its % distribution
A
  • fluid component of blood. makes up 55 % of blood (other 45% is cells)
  • fluid made up: water 91% / some proteins 7% / solutes 2%
    &raquo_space;proteins: albumin/globulin/fibrinogen
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16
Q

Albumin

  • what is it
  • role
A
  • one of proteins that compose plasma
  • maintains osmotic pressure
  • maintains water balance b/n tissues + blood
17
Q

Globulin

  • what is it
  • role
A
  • one of proteins that compose plasma
  • encompass important stuff for immune response: specifically, antibodies + complement
  • work transport molecules. carry hormones to organs
18
Q

Fibrinogen

  • what is it
  • role
A
  • one of proteins that compose plasma

- vital in CLOTTING mecahnism

19
Q

Solutes

  • which: HEGWIN = HEGWID
A
  • ions
  • nutrients
  • waste products
  • gases
  • enzymes
  • hormones
20
Q

Charles Drew

A
  • guy. african american.
  • studied blood plasma.
  • discoveries led to blood banks.
  • helped assuage fatalities in WWs.
  • Founded Red Cross Blood Bank