Blood and Hemostasis #4 9/17/15 Flashcards
What is the composition of blood?
45% Erythrocytes
55% plasma
What is one of the main limiting factors in erythropoiesis?
Availability of dietary iron
_____ serves as a storage buffer for iron.
Ferritin
What is the lifespan of a RBC?
120 days
______ is the major breakdown product of hemoglobin.
Bilirubin
_____ is only found in meat.
B12 * needed to make RBC’s
How is Erythropoiesis regulated?
Hormonally
Decreased oxygen delivery to the kidney causes _______________.
the secretion of erythropoietin, which activates receptors in bone marrow, leading to an increase in the rate of erythropoiesis.
What causes anemia?
Decrease in ability of RBC to carry oxygen due, to:
- decrease in the total # of RBC’s
- Diminished concentration of hemoglobin
What makes erythrocytes?
Erythropoietin