blood and blood vessels Flashcards
what separates blood
being spun in a centrifuge
components of blood =
erythrocytes ~45%
buffy coat (leukocytes and platelets) <1%,
plasma ~55%
what does plasma have
clotting factors
what removes clotting factors
serum
explain Erythrocytes (RBCs)
- Biconcave discs around 7µm in diameter
- No nucleus or organelles (when mature)
- Network of flexible cytoskeletal elements
explain Neutrophils
- 40-75% of WBCs
- Phagocytes (when activated)
- Single, multi-lobed nucleus
explain Eosinophils
- 5% of WBCs
- Acidic granules that stain red, and a bi-lobed nucleus
- Granules contain hydrolytic enzymes - inflammation
explain Basophils
- 5% of WBCs
- Basic granules that stain purple/blue, and a bi-lobed nucleus
- Effector cells in allergic reactions
explain Monocytes
- 1-5% of WBCs
- Precursors of tissue macrophages (phagocytes)
- Large, kidney bean-shaped nucleus
explain lymphocytes
- 0-50% of WBCs
- Small spherical nucleus and basophilic (blue) cytoplasm
B cells:
give rise to antibody secreting plasma cells
T cells:
differentiate in thymus, many defensive functions
what are platelets
Cell fragments that have a key role in haemostasis
Tunica intima: (structure of arteries)
single layer of squamous epithelial cells (endothelium) supported by a basal lamina and a thin layer of connective tissue
Tunica media: (structure of arteries)
predominantly made up of smooth muscle