blood and blood cells Flashcards

blood composition: list the major cellular and soluble components of blood, explain in simple terms their functions

1
Q

5 functions of blood

A

transport, heat distribution, immunity, homeostasis, haemostasis to decrease bleeding

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2
Q

4 components of blood

A

erythrocytes, leukocytes, plasma, platelets

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3
Q

leukocytes in order of concentration (low to high)

A

basophil, eosinophil, monocyte (macrophage), lymphocyte, neutrophil

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4
Q

features of erythrocytes

A

biconcave to increase SA:volume ratio, no nuclei or organelles, antigens on surface specific to group

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5
Q

name of erythrocyte production

A

erythropoiesis

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6
Q

types of phagocytes

A

polymorphonuclear granulocytes, monocytes, dendritic cells

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7
Q

types of polymorphonuclear granulocytes

A

neutrophil, eosinophil, basophil

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8
Q

function of neutrophil

A

engulf

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9
Q

functions of eosinophil

A

allergy and parasitic infections

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10
Q

functions of basophil

A

histamine causing anaphylaxis, inflammation, allergic response

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11
Q

features of polymorphonuclear granulocytes

A

multilobed nuclei, cytoplasmic granules, arrive first

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12
Q

general functions of polymorphonuclear granulocytes

A

kill pathogens, release inflammatory mediators, oxygen radicals, chemotaxins

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13
Q

features of monocytes

A

large nucleus, arrive later

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14
Q

what do monocytes mature into

A

macrophages

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15
Q

functions of macrophages

A

stimulate angiogenesis, role in immune response and inflammation within tissues, antigen-presentation

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16
Q

role of dendritic cells

A

antigen-presentation

17
Q

2 types of lymphocytes

A

B and T

18
Q

where do B-lymphocytes originate and mature

A

bone marrow

19
Q

what immunity are B-lymphocytes responsible for

A

humoral as release antibodies

20
Q

functions of antibodies (BACON)

A

binding, agglutination, coagulation, opsonisation, neutralisation

21
Q

what can B-lymphocytes become to provide a rapid 2nd response

A

B-memory cells

22
Q

where do T-lymphocytes originate and mature

A

bone marrow then thymus

23
Q

what do T-lymphocytes undergo in response to antigen binding

A

blast transformation

24
Q

what soluble mediators do T-lymphocytes release to also cause blast transformation

A

chemotaxins, lymphotoxin (cell), interferon (virus)

25
Q

what are platelets involved in

A

clot/thrombus formation

26
Q

what are platelets

A

cell fragments without a nucleus

27
Q

functions of plasma

A

fluid carrier, solvent for proteins (clotting, carrier molecules), exert osmotic pressure