Blood Administration and Transfusion Reactions Flashcards
requirements to donate blood
weight at least 110 lbs
be at least 17 years old
temp less than 99.6
types of blood donations
- directed: blood given for a specific person
- standard: blood given to anyone
- autologous: gives blood for self for later potential blood loss, can be saved for 10 years
- intraoperative blood salvage: blood is removed, filtered, and given back (unclosed system)
- hemodilution: intraoperative (closed system)
complication of donating blood
vagus syncope
universal donor
O-
universal recipient
AB+
pre-transfusion assessment
- previous reaction?
- received blood products?
- pregnancies?
- vital signs
- physical assessment
s/s of transfusion reaction
chills fever respiratory distress low back pain nausea pain at iv site unusual feeling
pre-transfusion procedure
- check written orders
- educate patient
- check id, name, and blood type (verified by two nurses)
- check the expiration date
- obtain second verifier to check blood info at the bed site in front of patient
- second nurse co-signs transfusion record
- label specimen at the bedside
- obtain vitals
- assessment
how to administer blood products
- use y-type tubing with a 170-260 micro-aggregate filter
- make sure tubing is primed with normal saline ONLY
- take vitals, begin transfusion
- stay with pt for at least the first 15 minutes
nursing management during reactions
- stop transfusion
- assess
- notify primary provider and implement prescribed treatment
- continue to monitor
- return blood
- obtain any samples
- document
post-transfusion procedure
- obtain vital signs
- dispose blood administration set appropriately
- monitor blood values as prescribed
- complete necessary post-transfusion paperwork
- document (if pt on i&o, total blood volume should be accounted for intake)
types of transfusion complications
- febrile nonhemolytic reaction
- acute hemolytic reaction
- allergic reaction
- circulatory overload
- bacterial contamination
- transfusion-related acute lung injury
- delayed hemolytic reaction
- disease acquisition
- long-term transfusion therapy
febrile nonhemolytic reaction
- caused by antibodies to donor wbc that remain in the unit of blood or blood component
- usually occurs 2 hours after start of transfusion
acute hemolytic reaction
- most dangerous
- occurs from incompatibility within first 10cc of blood transfused
- sx: fever, chills, low back pain, nausea, chest tightness, dyspnea, anxiety
allergic reactions
- itching, flushing, urticaria
- histamine response
circulatory overload
-too much products
bacterial contamination
- can occur anytime during process
- blood has to be transfused within 4 hours because the warmer the blood is the more bacteria grows
delayed hemolytic reaction
- can occur up to 14 days after the transfusion
- jaundice
long-term transfusion therapy
occurs with multiple transfusion patients such as anemia and sickle cell patients
pharmacologic alternatives to blood transfusions
- growth factors: increases the body’s production of blood cells
- erythropoietin: stimulates erythropoiesis for pt with chronic anemia
- granulocyte colony-stimulating factor: stimulates proliferation and differentiation of myeloid stem cells
- granulocyte- macrophage colony-stimulating factor: stimulates myelopoiesis
- thrombopoietin: increases platelet formation
packed red blood cells
- needs to be transfused within 4 hours
- used for hemorrhage, surgery, trauma, burn, shock, anemia
frozen RBC
- prepared from rbc using glycerol for protection and then frozen
- must be used within 24 hours of thawing
- used for autotransfusions: infrequently used because filters remove most of wbc
platelets
- needs to be transfused for 15-30 minutes
- bag must be agitated
- used for bleeding caused by the inability to coagulate
- reactions: febrile, sepsis
fresh frozen plasma
- liquid portion of whole blood
- transfuses for 30-60 minutes
- used for bleeding caused by deficiency in clotting factors
- reactions: acute hemolytic, febrile, mild allergic, hypervolemia, anaphylactic, sepsis
albumin
- prepared from plasma
- available in 5% (1-10 ml/min) or 25% (4ml/min)
- used for hypoalbuminemia
- reaction: hypervolemia, pulmonary edema
cyroprecipitates and commercial concentrates
- prepared form fresh frozen plasma
- used in treating hemophilia and for replacement of clotting factors, especially VIII and fibrinogen