Blood Flashcards

1
Q

Normal pH?

A

7.3 - 7.45

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2
Q

Plasma is an _ fluid

A

extracellular (ECF)

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3
Q

Blood comprises both

A

ECF and ICF (plasma and blood cells)

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4
Q

Blood helps maintain _

A

homeostasis

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5
Q

Fonctions of blood

A
  • transport
  • pH balance
  • protection
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6
Q

Hematocrit

A

% of blood volume occupied by RBCs

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7
Q

Normal hematocrit

A

45%

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8
Q

Normal blood volume

A

normovolemia

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9
Q

Lower blood volume

A

hypovolemia

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10
Q

higher blood volume

A

hypervolemia

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11
Q

% of body mass in reference individual

A

7%

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12
Q

Liters in reference individual

A

5L

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13
Q

Composition is similar to

A

ISF

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14
Q

Blood mainly composed by

A

Water (more than 90%)

+ significant amount of ions

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15
Q

In very small concentration in blood (exchange at capillaries)

A

Nutrients, wastes, respiratory gases

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16
Q

Main difference between blood and ISF compositions

A

Proteins (colloids, 7g/dL) in blood

17
Q

Percentage of colloids

A

Albumins 60%
Globulins 35%
Fibrinogen 5%

18
Q

Blood composition may be approximated by

A

physiological saline (0.9g/dL NaCl)

19
Q

Separation of plasma proteins by :

A
  • differential precipitation by salts
  • sedimentation in ultracentrafuge
  • electrophoretic mobility
  • immunological characteristics
20
Q

What is electrophoresis?

A

Fractional method based on mvt of charged particles along a voltage gradient
(Apply current to a drop of plasma)

21
Q

Rate of migration in electrophoresis influenced by:

A
  • number of protein
  • distribution of charges
  • molecular weight of protein