Blood Flashcards

1
Q

Blood matrix

A

Plasma

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2
Q

Blood formed elements

A

Erythrocytes, leukocytes, platelets

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3
Q

Amount of plasma in hematocrit

A

55%

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4
Q

Amount of buffy coat in hematocrit

A

1% and comprised of leukocytes and platelets

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5
Q

Amount of erythrocytes in hematocrit

A

45%

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6
Q

Define plasma

A

Straw colored sticky fluid that is 90% water with over 100 dissolved so lutes such as hormones wastes and proteins

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7
Q

Albumin

A

Makes up 60% of plasma proteins and functions as a carrier of other molecules, blood buffer and contributes to plasma osmotic pressure

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8
Q

RBC function

A

Respiratory gas transport

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9
Q

Hemoglobin

A

Binds reversibly with oxygen comprised of four polypeptide chains with a heme group attached to each one

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10
Q

Anemia

A

Blood has low O2 carrying capacity and could be caused by blood loss, not enough RBCs being produced or too many being destroyed

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11
Q

Polycythemia Vera

A

Bone marrow cancer leading to excess RBCs

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12
Q

Secondary polycythemia

A

Caused by low o2 levels like increased altitude or increased EPO production

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13
Q

Blood doping

A

Artificially injecting EPO or removing blood and reinfusing before an event

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14
Q

Leukocyte function

A

Defense agains disease

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15
Q

Diapedesis

A

Normal process of WBC leaving blood vessels to fight invaders in tissue

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16
Q

Granulocytes

A

Neutrophil, eosinophil, basophils

17
Q

Agranulocytes

A

Lymphocyte and monocytes

18
Q

Overproduction of abnormal WBC

A

Leukemia and mononucleosis

19
Q

Abnormally low WBC count

A

Leukopenia, which can be drug induced by anticancer drugs or glucocorticoids

20
Q

Platelet

A

Fragments of larger megakaryocyte

21
Q

Platelet function

A

Form temporary platelet plug that helps seal breaks in blood vessels

22
Q

Whole blood transfusion

A

Only used when blood loss is rapid and substantial

23
Q

Agglutinins

A

Pre formed anti A or anti B antibodies

24
Q

Antigen or agglutinogen

A

What immune system uses to identify blood cells

25
Blood typing chart
Review
26
Transfusion reactions
Occurs if mismatched blood is infused which results in new blood being attacked by plasma agglutinins which cam result in agglutinate and clogging blood cells and releasing hemoglobin into the blood stream via a rupture
27
Transfusion reaction complications
Diminished o2 carrying capacity Decreased blood flow behind blocked vessel Hemoglobin in kidney tubules can result in renal failure
28
If blood coagulates with serum then it
Contains that particular agglutinogen
29
Differential WBC count
Looks at the WBC count of the 5 leukocytes
30
Prothrombin time and platelet count
assesses homeostasis
31
CMP comprehensive medical panel
Blood chemistry profit checks various blood chemical levels that could indicate liver or kidney disorder
32
Complete blood count
Checks formed elements Hematocrit Hemoglobin