Blood Flashcards
Composition of blood
Fluid tissue - Leukocytes +Erythrocytes
Complex connective tissue.
Plasma
Platelets
Blood clotting haemostasis
Vascular spasm - smooth muscle contracts causing vasoconstriction
Platelet plug formation - injury to lining of vessel exposes collagen. platelets release chemicals to become sticky and plug, soluble.
Coagulation - fibrin forms a mesh, insoluble
RBC developmental formation
Stem cell - haemocytoblast
Committed cell - proerythroblast
Developmental pathway
Ribosome synthesis - early erythroblast
Haemoglobin accumulation - late erythroblast, hormoblast
Ejection of nucleus - hormoblast, reticulocyte
Erythrocyte in haematopoiesis
Erythropoieses
Antigens
RBC have different antigens on cell membrane.
Antigens are agglutinogins and proteins.
Can not have same type as antibody
Blood type based on antigen
Antibody
Antibodies are agglutinins.
In plasma.
If antibodies recognize matching antigens then agglutination occurs
Define haematocrit
ratio of volume of RBC to total blood
Where are monocytes produced
Spleen, liver and other organs
Haematology definition
The study, diagnosis and treatment of blood and blood diseases
Five functions of blood
Transports heat Transports nutrients, CO2 and O2 Transports waste and hormones Prevents infection Prevents blood loss
RBC
Erythrocytes
Testosterone produces more
Forms in red bone marrow at the end of long bones, from haemocytoblast stem cell
Forms in liver and spleen in foetus
WBC and function
Lymphocyte - produce antibodies and attack virus
Monocyte - Clean up damage and rid bacteria
Eosinohils - Involved in allergy and asthma
Basophils - release histomine, inflammatory
Neutrophils - eats cells by phagocytosis
Difference between total WBC count and differential WBC count
WBC count measures number of WBC.
Differential is the percentage of each type of WBC in blood
Bone marrow
Produces
RBC
Granulocytes
Platelets
Haematopoiesis definition
The dividing of haemocytoblast into three groups
Erythrocyte
Leukocyte
Thrombocyte