Blood Flashcards

1
Q

Composition of blood

A

Fluid tissue - Leukocytes +Erythrocytes
Complex connective tissue.
Plasma
Platelets

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2
Q

Blood clotting haemostasis

A

Vascular spasm - smooth muscle contracts causing vasoconstriction
Platelet plug formation - injury to lining of vessel exposes collagen. platelets release chemicals to become sticky and plug, soluble.
Coagulation - fibrin forms a mesh, insoluble

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3
Q

RBC developmental formation

A

Stem cell - haemocytoblast
Committed cell - proerythroblast
Developmental pathway
Ribosome synthesis - early erythroblast
Haemoglobin accumulation - late erythroblast, hormoblast
Ejection of nucleus - hormoblast, reticulocyte

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4
Q

Erythrocyte in haematopoiesis

A

Erythropoieses

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5
Q

Antigens

A

RBC have different antigens on cell membrane.
Antigens are agglutinogins and proteins.
Can not have same type as antibody
Blood type based on antigen

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6
Q

Antibody

A

Antibodies are agglutinins.
In plasma.
If antibodies recognize matching antigens then agglutination occurs

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7
Q

Define haematocrit

A

ratio of volume of RBC to total blood

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8
Q

Where are monocytes produced

A

Spleen, liver and other organs

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9
Q

Haematology definition

A

The study, diagnosis and treatment of blood and blood diseases

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10
Q

Five functions of blood

A
Transports heat
Transports nutrients, CO2 and O2
Transports waste and hormones
Prevents infection
Prevents blood loss
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11
Q

RBC

A

Erythrocytes
Testosterone produces more
Forms in red bone marrow at the end of long bones, from haemocytoblast stem cell
Forms in liver and spleen in foetus

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12
Q

WBC and function

A

Lymphocyte - produce antibodies and attack virus
Monocyte - Clean up damage and rid bacteria
Eosinohils - Involved in allergy and asthma
Basophils - release histomine, inflammatory
Neutrophils - eats cells by phagocytosis

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13
Q

Difference between total WBC count and differential WBC count

A

WBC count measures number of WBC.

Differential is the percentage of each type of WBC in blood

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14
Q

Bone marrow

A

Produces
RBC
Granulocytes
Platelets

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15
Q

Haematopoiesis definition

A

The dividing of haemocytoblast into three groups
Erythrocyte
Leukocyte
Thrombocyte

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16
Q

Rhesus factor

A

Rhesus antigen.
Another group of antigens on surface of RBC
No natural RH
Problematic in pregnancies

17
Q

Haematocrit value

A

RBC\total blood *100

18
Q

Difference in solvent and plasma

A

Solvent - platelets = plasma

19
Q

Plasma structure

A

90% water
10% solute
cells, gasses, hormones, proteins, electrolytes

20
Q

Leukopoiesis.

A
Divides into
Lymphocytes
Monocytes
Eosinphil
Basophil
Neutrophil
21
Q

Leukocytes Granulocytes

A
Granulocytes contain granules.
Neutrophil
Basophil
Eosinphil
Agranulocyes do not
Monocyte
Lymphocyte
22
Q

Stem cell (haemocytoblast)

A
Developmental pathway
Megakaryoblast
Promegakaryocyte
Megakaryocyte
Platelets
23
Q

Which substance makes the plasma so sticky?

A

Platelets

24
Q

How would the haematocrit change if a person lost a lot of body fluids?

A

Haematocrit value would be higher- higher % of RBC in blood- Dehydrated

25
Q

Function of platelets

A

for clotting: circulate within blood and form a platelet plug when a damaged vessel is recognised. Clot

26
Q

What are the three main proteins found in blood?

A

albumins, globulins and fibrogen

27
Q

What is the definition of a formed element?

A

red blood cells, white blood cells, and platelets.

28
Q

How is type A blood different from type blood B blood?

A

A blood has A antigens, B blood has B antigens.

29
Q

How is type AB blood different from types A and B blood?

A

AB blood carries both A and B antigens