Blood Flashcards
Which type of blood cell carries oxygen and carbon dioxide?
RBC
Which type of blood cell participates in immunological responses?
WBC
Which type of blood cell promotes clotting?
platelets
5,000 to 10,000 per uL
WBC
4 to 5 million per uL
RBC
12 to 16 grams per dL*
HGB
40 to 50 %*
HCT
150,000 to 400,000 per uL
Platlets
What are these?
RBCs
(60-70%) increased with acute infection –
Neutrophils
(20-30%) increased with chronic infection –
Lymphocytes
(3-8%) may be increased during infection –
Monocytes
(2-4%) increased with chronic allergy, parasitic worms
Eosinophils
(<1%) usually constant
Basophils
What type of WBC is this?
Neutrophil
What type of WBC is this?
Eosinophil
What type of WBC is this?
Basophil
What type of WBC is this?
Lymphocyte
What type of WBC is this?
Monocyte
What are these?
platelets
- Cell fragments 2–4 µm in diameter derived from megakaryocytes of bone marrow.
- Release the content of their granules upon contact with collagen
- Promote clot formation and reduce blood loss from the vasculature
platelets
- 3-8% of WBC.
- 12—20 microns in size.
- Actively phagocytic and MOTILE cell, use diapedesis. •Large nucleus, indented on one side.
- Presence in blood is temporary.
- Lysosomes in cytoplasm. •
monocyte
- 20-30% of WBCs :
- Small (90%), Medium, Large 6-18 u
- Round nucleus, round cell, thin rim of cytoplasm.
- Three indistinguishable types in smears: T and B –90% in blood are T cells, remainder are B cells or –Natural Killer cells (no markers of either T or B) –Immunocytochemical staining for surface receptors used to identify T and B cells.
lymhocyte
- 25-200 per microliter. 0-1% of leukocytes.
- Nucleus bilobed, may be masked by granules.
- Large, BASOPHILIC granules, 10-100 per cell
- Contain HISTAMINE, HEPARIN, ECF
- Act to dilate vessels and increase vascular permeability •Closely related to Mast Cells
Basophils
- 100—400 per microliter, 2-4% of WBCs
- Bilobed Nucleus
- Motile cell capable of diapedesis
- Live for few days, 30 hrs spent in circulation
- Associated with ALLERGIC RXNS, PARASITES
- Common in dermis, bronchial tree, vagina, uterus, alimentary tract
Eosinophils
- Multilobulated nuclei : polymorphonuclear leukocytes •approximately twice that of the surrounding erythrocytes •Pale (neutral) granules
- Phagocytosis and oxidative bursts
- Can damage tissue
Neutrophils
-99% of blood cells •
- Biconcave Disk- advantageous shape
- Anucleate in mature form
- Elastic, readily deform, rebound easily
- Spectrin binds to inner part of plasmalemma with actin filaments to maintain shape of cell
- essentially Hemoglobin bounded by plasmalemma
Erythrocytes (RBCs)
projections extending from a smaller central area of a RBC, like a spiked ball. These may be either large, irregular spicules of acanthocytes, or smaller, more numerous, regularly irregular projections.
crenated RBC
- RBCs sticking together
rouleaux
middle portion of RBC looks slighter since its thinner
central pallor
different sizes of RBCs
anisocytosis
what is the moelcule used iby macrophages to identify worn out RBCs?
Band 3
what is a reticuloycte?
an immature RBC
