BLOOD Flashcards
How much blood in adults
5 liters (70ml/kg) in males 65ml/kg in females
Blood consists of…
Plasma, red blood cells, white blood cells, and platelets
Plasma
Watery fluid that accounts for more than half of the total blood volume. 92% water, 8% dissolved substances
Erythrocytes
Red blood cells. Carries oxygen to the cells. Propelled by plasma. Contain hemoglobin.
Hemoglobin
In red blood cells. Binds oxygen absorbed in the lungs.
Erythropoiesis
The process that makes red blood cells.
Microphages
Cells that protect the body against infection.
Bilirubin
RECYCLING PARTS OF HEMOGLOBIN. Leftover parts of the hemoglobin that are not destroyed, is converted into bilirubin… Which undergoes further metabolism in the liver.
Antigens
Proteins recognized by the immune system.
Antibodies
Proteins that react with antigens .
Blood typing
Classified based on the presence or absence of specific antigens. Four blood types.
Anemia
Decrease in the he number of red blood cells.
Erythroblastosis fetalis
During late pregnancy and delivery… The mother and fetus may have different Rh positives/negatives. Mothers body’s will produce antibodies to the antigens, which may enter the fetal circulation and destroy the fetus red blood cells.
Leukocytes
White blood cells
Fight infections.
Larger than red blood cells
Diapedesis
Allows white blood cells (leukocytes) to leave the blood vessels and go to the tissues where they may be needed.
Two types of leukocytes…?
Granulocytes
Agranulocytes
Neutrophils
Most common type of granulocytes. Polymorphonuclear cells (polys). DESTROY BACTERIA
Eosinophils
Function in allergic responses.
Basophils
Play a role in allergic and inflammatory reactions.
Contain large amounts of histamine .
Histamine
Substance that increases tissue inflammation.
Heparin
Substance that inhibits blood clotting
Lymphocytes
Smallest of the Agranulocytes.
Most originate in the lymph nodes.
Monocytes
Respond to infections and are thence first line of defense in the inflammatory process
Platelets
Cells within the blood.
Essential for clot formation.
Hemostasis
Cessation of bleeding… The process in he hitch bleeding stops and a final clot is formed.
Fibrin
Binds to the platelet plug ( aggregated platelets cause an initial plug to stop bleeding) to create the final mature clot.
Tissue plasminogen activator
“T-Pa”
Counterbalances they clotting system.