Blood

Question 1

What is blood made up of?

Answer 1

• 55% plasma
• 45% red blood cells
• <1% white blood cells
• < 1% platelets

Question 2

How are red blood cells made? Erythropoiesis

Answer 2

Starts in bone marrow as pluripotent stem all, which then differentiates into eryth roblast. Haemoglobin is made and nucleus removed (reticulocyte). Which then matures after leaving bone marrow to form erythrocyte.

Question 3

While blood cells

Answer 3

• Nave a nucleus
• combat infection by phagocytosis or by immune response
• can leave blood stream to deal with invading pathogens

Question 4

Platelets

Answer 4

• Formed from megakaryocytes
• disc shaped
• no nucleus
• life span 5-9 days

Question 5

Blood groups

Answer 5

Categorised by presence or absence of antigens on surface cell
A, B, AB (can transfuse with any type of blood), O (can be donated to anyone)

Question 6

Rhesus incompatibility

Answer 6

If mother is Rh- and fetes is rh+, mother requires anti D. Will attack the foetal erythrocytes carrying D surface antigen