Blood Flashcards

1
Q

What are the two circulatory systems?

A

Pulmonary and Systemic

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2
Q

What are the three components of the Cardiovascular system?

A

Heart, Blood, and Blood vessels

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3
Q

Whats the fxn of the heart?

A

Pump blood through the body

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4
Q

Whats the fxn of the blood?

A

Transport of gases, nutrients, and waste.

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5
Q

Whats the fxn of blood vessels?

A

To receive the blood and collect what is carrying.

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6
Q

What molecules are transported by blood?

A

Gases(O2, CO2), hormones, proteins, and waste products

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7
Q

How is blood pH maintained?

A

Hemoglobin and albumin act as a buffer to blood ph, keeping it between 7.35 and 7.45

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8
Q

What makes up blood?

A

Formed elements and plasma.

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9
Q

Whats the major function of formed elements?

A

Increase immune function, Carry O2, and help with clotting.

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10
Q

Whats the major function of plasma

A

Plasma helps keep the blood less viscous and carry proteins

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11
Q

What is formed elements made of?

A

Erythrocytes, Leukocytes, and thrombocytes.

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12
Q

What is the hematocrit?

A

It is the the cell volume when compared to the total volume of blood

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13
Q

What does a high and low hematocrit mean?

A

High mean blood is too viscous and the heart is working too hard, while a low hematocrit means it doesn’t have enough RBC to carry O2

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14
Q

What is polycythemia?

A

When the hematocrit is too high

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15
Q

Whats the function of Erythrocytes

A

To carry oxygen, also most numerous.

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16
Q

Whats the function of leukocytes?

A

They are the main contributes to immune function, also least common

17
Q

What is the function of thrombocytes?

A

To help with clotting

18
Q

Describe a RBC

A

It has no nucleus or mitochondria, has a bi-concave disk in the center, and features hemoglobin.

19
Q

What is hemoglobin?

A

It makes up 1/3 of the RBC and is the pigment that carries O2 in RBCs

20
Q

What is a hemocytoblast?

A

It’s the stem cell that all blood cells are derived. They are located in RBM

21
Q

What is anemia?

A

It is when the blood has a decreased capacity to carry oxygen, possibly causing some tissues to not get enough O2

22
Q

What is erythropoietin?

A

It is the hormone that is produced predominantly by specialized cells of the kidney, and it stimulates RBC synthesis in RBM

23
Q

What happens when a erythrocyte is recycled?

A

It is degraded in a macrophage, being phagocytosed into a heme and globin, which is turned into amino acids and iron.

24
Q

What is bilirubin? What is it derived from?

A

Bilirubin is a yellow molecule that is toxic if left within certain parts of the body. It is incorporated with bile in the liver. Derived from biliverdin.

25
Where is iron stored? Why is iron important?
Stored in bone marrow and the liver, and its important because it makes up heme in hemoglobin.
26
What are the five types of leukocytes?
Neutrophils, Eosinophils, Basophils, Lymphocytes, and monocytes.
27
What is visual difference of each leukocyte?
Neutrophils: Many Nuclei Eosinophils: Bilobed nucleus Basophils: Big blob that won't come into focus Lymphocytes: Large round nucleus Monocytes: Heart or kidney shaped
28
What does each leukocyte do?
Neutrophils: Phagocytosis Eosinophils: Phagocytosis and anti-inflammatory chemicals Basophils: Phagocytosis and production of histamine and heparin. Lymphocytes: T and B cells Monocytes: Phagocytosis and macrophages.
29
How are thrombocytes produced?
They are cell fragments from megakaryocytes.
30
What re the three stages of clotting?
There is vascular spasm(Vasodilation), Platelet plug, and Coagulation
31
Intrinsic vs. Extrinsic clotting
Intrinsic is activated by internal damage while extrinsic is activated by the tissue thats damaged. Both result in coagulation.
32
What are clotting factors?
They are proteins that form blood clots to stop bleeding.
33
Why don't clots just form in our veins and arteries?
There is naturally forming anti-coagulants in blood
34
What protein stabilizes blood clots?
Fibrogen
35
What is hemophilia?
Impaired ability for blood to clot.
36
What the difference in a thrombus and embolism?
Thrombus is stationary, while embolism is a traveling blood clot
37
How do various anticoagulants prevent clots from forming inapproprately?
Inhibiting clotting factors, thromboxane, and breaks clots already formed.