BLOOD Flashcards
The only fluid tissue in the body
Blood
Specialized connective tissue in which living blood cells
Formed elements
suspended in a nonliving fluid matrix
Plasma
Total blood volume in an average adult is about:
4-5 liters in females and 5-6 liters in males.
the total weight of the body
8%
Blood components
- Withdraw bloof and place in tube.
- Centrifuge the blood sample.
- Formed elements
Formed elements:
Plasma
Buffy coat
Erythrocytes
55% of whole blood and least dense component
Plasma
Leukocytes and platelets, 1% of whole body.
Buffy coat
45% of whole blood (hemotocrit), most dense component.
Erythrocytes
Blood - Physical Characteristics:
• Sticky, opaque fluid with a metallic taste
• Color varies from scarlet to dark red.
• Blood is denser than water and about five times more viscous, largely because of the formed elements.
• Slightly alkaline (pH – 7.35-7.45)
Functions of blood:
Protection > Distribution > Regulation > Protection
A pale - yellow fluid that consists of about:
• 91% water
• 7% proteins
• 2% other solutes
Plasma
Plasma consists of
• 91% water
• 7% proteins
• 2% other solutes
Plasma proteins includes:
• Albumin
• Globulin
• Fibrinogen
Contributes to osmotic pressure
Albumin (58%)
Composed of gamma, alpha and beta
Globulin (38%)
Contributes to blood clot
Fibrinogen (4%)
The process of blood cell production
Hematopoiesis
All the formed elements of the blood are derived from a single population of cells
Stem cells
Stem cells composed of:
• 95% of red blood cells (erythrocytes)
• 5% of white blood cells (leukocytes) and blood platelets (thrombocytes)
Red Blood C
Biconcave disk, no nucleus, contains hemoglobin which colors the cell red.
Red Blood Cells (Erythrocytes)
6.5-8.5 micrometer in diameter.
Red Blood Cells (Erythrocytes)
A microliter of blood contains
5 million of red blood cells.
A microliter of blood contains 5 million of red blood cells.
Red Blood Cells (Erythrocytes)
Function: Transports oxygen and carbon dioxide
Red Blood Cells (Erythrocytes)
Red Blood Cells (Erythrocytes)
a. Hemoglobin consists of globin (two alpha and two beta polypeptide chains) and four heme groups.
b. Iron-containing heme pigment.