Blood Flashcards

1
Q

blood is which type of tissue

A

special connective tissue

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2
Q

what does blood contain

A

fluid marix called plasma
formed elements

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3
Q

what colour is plasma

A

straw coloured

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4
Q

how much percent of blood is plasma

A

55

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5
Q

plasma is how much percent water and how much percent proteins

A

90-92
6-8

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6
Q

major proteins in plasma

A

fibrionogen
globulins
albumins

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7
Q

function of fibrinogen

A

clotting / coagulation of blood
(present in inactive form)

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8
Q

function of globulin

A

involved in defense mechanisms of body

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9
Q

function of albumin

A

help in osmotic balance

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10
Q

what minerals are also present in plasma in small amounts

A

Na+, Ca++, Mg++, HCO3-, Cl-, etc

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11
Q

plasma without fibrinogen is called

A

serum

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12
Q

what are formed elements

A

erythrocytes
leucocytes
platelets

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13
Q

how much percent of blood are formed elements

A

45

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14
Q

which is the most abundant of all cells in blood

A

erythrocytes

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15
Q

how many rbcs does a healthy man on average have

A

5 to 5.5 million per mm^3 of blood

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16
Q

where are rbcs formed in adults

A

red bone marrow

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17
Q

do rbc have a nucleus
what is their shape

A

no
biconcave

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18
Q

iron containing protein in rbc

A

haemoglobin

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19
Q

how much haemoglobin does a healthy person have

A

12 to 16 gm per 100 ml of blood

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20
Q

average lifespan of rbc

A

120 days

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21
Q

where are rbc destroyed and what is that organ called

A

spleen
graveyard of rbcs

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22
Q

why are leucocytes colourless

A

due to lack of haemoglobin

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23
Q

do wbc have a nucleus

24
Q

how many wbc does a healthy person have

A

6000 to 8000 per mm^3 of blood

25
two main categories of wbc
granulocytes agranulocytes
26
granulocytes
neutrophils eosinophils basophiles
27
agranulocytes
lymphocytes monocytes
28
which cell is most abundant of total wbc in blood and which is the least
neutrophils (60 - 65%) basophils (0.5 - 1%)
29
which wbc are phagocytic
neutrophils monocytes
30
percentage of monocytes in blood
6-8
31
function of basophil
secretion of histamine, serotonin, heparin involved in inflammatory reactions
32
percentage of eosinophils in blood
2-3
33
function of eosinophils
resist infections associated with allergic reactions
34
percentage of lymphocytes
20-25
35
two major types of lymphocytes
B and T
36
function of lymphocytes
immune responses of body
37
platelets are also called
thrombocytes
38
how are platelets produced
platelets are cell fragments produced from megakaryocytes which are special cells in the bone marrow
39
amount in platelets in blood
1,50,000 to 3,50,000 per mm^3
40
what does reduction of platelets lead to
clotting disorders which will lead to excessive loss of blood from body
41
widely used groupings of blood
ABO and Rh
42
what are antigens
chemicals that induce immune response
43
two antigens on rbc in ABO grouping
A B
44
if imcompatible blood is accidentally transfused to a recipient, what happens
clumping of blood (destruction of rbc)
45
four blood groups in ABO grouping
A B AB O
46
universal donor
O
47
universal recipient
AB
48
in Rh grouping, Rh antigen on rbc is similar to one present in which animal
rhesus monkey
49
special case of Rh incompatibility
Rh-ve blood of pregnant mother with Rh+ve blood of foetus
50
the imcompatible blood of mother and foetus are well separated by which organ
placenta
51
when is there a possibility of incompatible blood of mother and foetus mixing and what happens
during delivery mother starts preparing antibodies against Rh antigen
52
what about her subsequent pregnancies
Rh-ve blood of mother could leak into blood of Rh+ve foetus and destroy foetal rbcs fatal to foetus or could cause severe anaemia and jaundice
53
Rh-ve blood of mother could leak into blood of Rh+ve foetus and destroy foetal rbcs this condition is called
erythroblastosis foetalis haemolytic disease of new born
54
how can erythroblastosis foetalis be avoided
by administering anti-Rh antibodies to mother immediately after delivery of first child rhogam vaccine
55
with what is a clot or coagulam formed
network of threads called fibrins
56
how are fibrins formed
platelets release substances to start a cascade process to form enzyme thrombokinase which surpervises prothrombin to thrombin enzyme thrombin supervises fibrinogen to fibrins calcium ions are required in each step
57
how is mechanism of clotting stimulated
injury or trauma stimulates platelets in blood to release certain factors