blood Flashcards

1
Q

what does blood transport (7 things)

A

gases, waste products of metabolism, hormones, nutrients, plasma proteins, blood cells

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2
Q

what does blood regulate?

A

body fluid electrolytes

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3
Q

how does the blood protect the body?

A

removes toxins, regulates blood clotting

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4
Q

what is the ph of blood

A

7.35 - 7.45 (slightly alkaline)

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5
Q

what are the three components of blood (and their proportions)

A

red blood cells (44%), white blood cells and platelets (1%), plasma (55%)

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6
Q

science name for red blood cells

A

erythrocytes

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7
Q

science name for white blood cells

A

leukocytes

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8
Q

science name for platelets

A

thromocytes

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9
Q

what types of RBCs are found in iron deficiency anaemia?

A

microcytic

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10
Q

what types of RBCs are found in folate deficiency anaemia?

A

macrocytic

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11
Q

what is the structure of haemoglobin

A

4 protein chains; 2 alpha, 2 beta. contains 2 iron containing ham groups

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12
Q

what Is the name of the molecule when oxygen is bound to haemoglobin

A

oxyhaemoglobin

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13
Q

in the lungs, what does the partial pressure of oxygen mean for Hb saturation

A

nearly 100% saturated with oxygen

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14
Q

which part of Hb is mutated in sickle cell anaemia

A

the beta chain is mutated

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15
Q

can carbon dioxide bind to Hb

A

yes

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16
Q

what is haemostasis

A

the arrest of bleeding from a broken blood vessel

17
Q

what are platelets

A

small cell fragments, anuclear

18
Q

what are the 3 steps of haemostsis

A

1) vascular spasm
2) formation of platelet plug
3) blood coagulation/clooting

19
Q

during vascular spasm, what happens to the blood vessels and muscle layer?

A

blood vessel constrict. Muscle layer surrounding a cut blood vessel immediately constricts slowing blood flow

20
Q

what do platelets use to to form a platelet plug?

A

von Willebrand’s factor - a plasma protein secreted by endothelial cells and platelets

21
Q

what do platelets bind to in order to become sticky

A

collagen

22
Q

what does vessel lining normally release to inhibit platelet aggregation

A

prostacyclin - means platelet plug does not spread to normal tissue

23
Q

what do clots form on top of and why

A

platelet plugs, to strengthen, support and reinforce it

24
Q

fibrinogen is converted to … by enzyme … to form clot

A

fibrin, thrombin

25
Q

why does the body have an anti-clotting system

A

to inhibit abnormal clotting

26
Q

name 4 causes of abnormal clotting

A

blood stasis, injury to vessel wall, thrombogenic changes in blood, inherited coagulopathies

27
Q

name the 4 blood groups

A

A, B, AB, O

28
Q

when the plasma of blood group A is missed with the RBCs of a blood group B persons, what happen?

A

the anti-B antibodies in the plasma cause clumping of the RBCs

29
Q

what is a blood group

A

a classification of blood based on the presence of inherited antigenic substances on the surface of a RBC