Block 3 Flashcards
QT interval
- Normal =
QT & HR
- Inversely related
- HR decreases, QT increases
- Women larger interval than men
Calculation of QT upper limit by HR
60 BPM = 0.4 (men), 0.44 (women)
- Subtract 0.02 for every 10 BPM
100 BPM = 0.31 (m), 0.34 (w)
Ischemic stroke
- Occlusion of artery in brain region
- 87% of all strokes
Hemorrhagic stroke
- Ruptured blood vessel
- Avoid coagulants
- 13% strokes
8 Ds of stoke care
- Detection: recog sx
- Dispatch: Activation & EMS
- Delivery: EMS ID, mgmt, transport
- Door: triage at stroke center
- Data: triage, eval and mgmt in ED
- Decision: expertise and therapy selection
- Drug: fibrinolytic, intra-arterial
- Disposition: admit to stroke unit
Diltiazem- MOA
Calcium channel blocker
Diltiazem- Indications
- A fib & A flutter
- Refractory SVT conversion
Diltiazem- AE/ CI
- Wide QRS
- Wolffe- Parkinson white
- Beta blockers
Furosemide- MOA
Loop diuretic
Furosemide- Indications
- Pulmonary edema
- Hypertensive emergencies
Furosemide- AE/CI
Dehydration, hypovolemia, hypotension
Verapamil- MOA
CCB
Verapamil- Indications
- A fib, A flutter
- SVT prevention
Isoproterenol- MOA
Phosphodiesterase enzyme inhibitor
Isoproterenol- Indications
Severe CHF refractory to diruetics, vasodilators and inotropes
Isoproterenol- AE/CI
Do not mix with dextrose
- Causes tachy arrthmias, hypotension, MI
Lidocaine- MOA
Antiarrythmic, inhibits NA ion channels
Lidocaine- Indications
Amioderone alternative in cardiac arrest
- VF/ VT
Lidocaine- AE/ CI
- Not for prophylaxis in AMI
- reduce dose with liver dysfunction, LV
Procainamide- MOA
Antiarrythmic
Procainamide- Indications
- Wide variety of arrthymias
- A fib, wolffe parkinson white
- Vtach, reentry SVT
Procainamide- AE/CI
- Proarrthymic
- Induces hypotension
- Prolongs QT interval
Adenosine- MOA
Antiarrythmic, interrupts AV node reentry
Adenosine- Indications
Tachycardia
Adenosine- AE/ CI
- AV blocks, sinus node disruptions
- Cardiac arrest, bradycardia
Diazepam- MOA
Benzodiazapine
Diazepam- Indications
Procedural sedation
Diazepam- AE/CI
- Resp depression, abuse
- Drowsiness, fatigue
tPA- MOA
Binds to fibrin, activating plamin. Clot lysis
tPA- Indications
- Within 3 - 4.5 hours of ischemic stroke
- Neuroimpairment
tPA- AE/ CI
- Hemorrhage, bleeding disorders
- HTN > 185/110