Block 3

Question 1

What is blastomycosis?

Answer 1

Saprobes (causative agents) in nature or in soil
“Endemics”
“True pathogens”; in healthy hosts (how it got its name)
Endemic fungi in the US
Basically purple is the overlap of two organisms
Green is of the coccidioides
Blastomyces dermatitis
Infection of the lungs
Morph; yeast
Conidia
Thick cell wall

Question 2

What is histoplasmosis?

Answer 2

Darling’s disease
Systemic mycosis
Severe biohazard in lab
One in africa
Other one is the more common one 
Both human varieties 
Mimics TB (acute pulmonary)

Question 3

What is paracoccidiodes?

Answer 3

Saprobe (in nature/soil) room temp (approx 25 degrees celsius
Parasitic at body temp (37 degrees celsius)
Paracoccidioides lutzii
Intracellular pathogen
Add para in front of the coccidioides 
Yeast; ascomycetous
Serodiagnostic exam 
Skin test (geographical distribution)
“Pilots wheel”
High incidences of oral lesions
Armadillos; do not transmit the disease to humans
CNS; more frequent