Block 12 Flashcards

1
Q

Inability to recognize faces

A

Prosopagnosia

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2
Q
  • dorsal processing
  • parietal path
  • where path

They scribe the visual path that processes what

A

Process motion

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3
Q

Optic ataxia may result from damage in which cortical processing stream

A

Dorsal-dorsal

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4
Q

Inability to point or reach for a target

A

Optic ataxia

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5
Q

Form of attention that alerts you when another vehicle swerves into your lane

A

Bottom up

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6
Q

Form of attention from an external source

A

Bottom up

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7
Q

Observer controls what they are attending to

A

Top down

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8
Q

Clinical condition that may be caused by abnormal connections between cortical modules

A

Synaesthesia

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9
Q

Damage to inferotemporal cortex may result in deficits in analyzing what

A

Form

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10
Q

Akinetopsia may result from damage to

A

Area v5

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11
Q

As the number of distractions increases, the ability to detect the salient objects

A

Remains the same

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12
Q

Shifts in attention alter the responses of cells located where

A

Area v4

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13
Q

Type of attention: looking for a friend in a crowd of people

A

Top down

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14
Q

Type of attention: responding to the slamming of the door

A

Bottom up

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15
Q

Type of attention: searching for quarters in a drawer of loose change

A

Top down

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16
Q

Prosopagnosia is most likely to be accompanied by

A

Achromatopsia

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17
Q

Cortical areas that are a part of the ventral processing system

A

IT and V4

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18
Q

Inability to perceive 2 objects simultaneously

A

Simultagnosia

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19
Q

Visual hallucinations experienced in Charles bonnet syndrome have been compared to

A

Phantom limb syndrome

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20
Q
  • Demonstrated in elderly people

- used to treat amblyopia

A

Perceptual learning

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21
Q

How many areas of the brain are distinct visual areas

A

20

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22
Q

Each visual area has what

A

A retinotopic map

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23
Q

Are the processing streams independent of each other

A

No

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24
Q

Which stream is critical for identifying and recognizing objects

A

Temporal, ventral, what stream

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25
Q

Which stream plays a role in motion perception, localization in visual space, and action organization

A

Dorsal, parietal, where stream

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26
Q

2 parts of the dorsal stream

A

Dorsal-dorsal stream

Ventral-dorsal stream

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27
Q

Which arm of the dorsal stream processes action info

A

Dorsal-dorsal stream

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28
Q

Damage to the dorsal-dorsal stream may result in

A

Optic ataxia

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29
Q

Inability to point to or reach for a visual target

A

Optic ataxia

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30
Q

Which arm of the dorsal stream includes extrastriate area MT/V5

A

Ventral-dorsal

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31
Q

Which arm of the dorsal stream plays a role in space perception and action organization

A

Ventral-dorsal

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32
Q

The parvo path has strong input to

A

Ventral stream

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33
Q

Mango path inputs mainly to which stream

A

Dorsal stream

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34
Q

Which retinogeniculate pathways may provide input to

A

Both corical processing streams

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35
Q

Area that has an abundance of cells with chromatic sensitivities

A

V4

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36
Q

Cells in which area respond to complex forms, including faces

A

IT

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37
Q

This area is well adapted to color perception

A

V4

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38
Q

The area plays a role in form perception

A

IT

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39
Q

V4 and IT are part of which stream

A

Ventral

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40
Q

Areas MT/V5 are a part of which stream

A

Dorsal

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41
Q

Which imaging technique has better resolution: fMRI or PET

A

fMRI

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42
Q

Which imaging technique uses a radioactive tracer to observe changes in blood flow indicating increased cortical metabolism

A

PET

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43
Q

Which imaging technique reveals cortical activity by detecting levels of oxygenation (BOLD- blood oxygen level dependent)

A

fMRI

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44
Q

If asked to view a certain color, but stream may have elevated activity

A

Ventral

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45
Q

If asked to focus on the shape or form of an object, which stream becomes active

A

Ventral

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46
Q

If asked to focus on the movement of on object, which stream will have increased activity

A

Dorsal

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47
Q

Motion and position are processed along

A

Dorsal

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48
Q

Color and form info are processed along

A

Ventral

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49
Q

Integration of the info from dorsal and ventral with memory is coordinated by

A

Prefrontal cortex

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50
Q

Area been though to play a role in cognition

A

Prefrontal cortex

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51
Q

Cells in the MT/V5 are capable of analyzing

A

Motion info

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52
Q

The movement of a plaid pattern (an integrated stimulus of 2 components) appears as a

A

Single object moving in an intermediate direction by area MT/V5

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53
Q

What area has also been studied with random dot kinematograms

A

MT/V5

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54
Q

MT/V5 is more active when viewing what kind of object

A

Moving object

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55
Q

A motion illusion that occurs in the absence of motion

A

MAE (motion aftereffect)

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56
Q

Motion detectors mediating the MAE are located

A

In the cortex

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57
Q

Where it’s he first site of substantial interaction between the2 eyes

A

Cortex

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58
Q

Size of receptive fields of cells in IT

A

Large

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59
Q

Cells in IT respond best to

A

Sophisticated shapes

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60
Q

Which cells respond best to bars, edges and gratings

A

Cells in the striate cortex

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61
Q

Area of the brain that responds well to objects, but not scrambled objects or object fragments

A

LOC (lateral occipital complex)

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62
Q

What area of the brain responds well to faces, but not other objects

A

FFA (fusiform face area)

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63
Q

Which area of the brain is strongly activated by objects and places, but not faces

A

PPA (parahippocampal place area)

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64
Q

What cortical area processes:
1- face
2- color

And are in close proximity

A

1- FFA

2-V4

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65
Q

Pts who suffer from prosopagnosia may also manifest what (because of location of brain areas)

A

Cerebral achromatopsia

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66
Q

This form of attention is volitional

A

Top down

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67
Q

Directing our attention on each object of interest to see what is available is an example of

A

Serial processing

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68
Q

What type of processing facilitates detection of the salient feature

A

Preattentive processing

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69
Q

Phenomenon in which we cannot readily see the difference between 2 images

A

Change blindness

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70
Q

What condition can make changes between 2 images more visible

A
  • presented in rapid sequence (triggers our exogenous attention)
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71
Q

What condition can make changes between 2 images less visible

A

2 images presented simultaneously (dont as readily elicit our attention)

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72
Q

Which area of the brain is involved in topdown visual attention

A

Prefrontal cortex

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73
Q

Do cells in the striate cortex demonstrate topdown attention

A

No

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74
Q

Lesions in the striate cortex produce

A

Simple blind spots (scotomas)

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75
Q

Extrastriate lesions can lead to

A

Visual agnosia

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76
Q

Defect in the perception of motion

A

Akinetopsia

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77
Q

Where is the damage in akinetopsia

A

Dorsal processing stream

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78
Q

Lesions to the superior temporal lobe can lead to

A

Visual neglect (only recognize one side - only eat one half of plate, only shave one side of face, etc)

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79
Q

Not able to percieved more than one object at a time

A

Simultagnosia

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80
Q

Simultagnosia may be seen in pts with what syndrome

A

Balint’s syndrome

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81
Q

Condition where there is bilateral damage to parietal lobes

A

Balint’s syndrome

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82
Q

The presentation of a letter or number results in the perception of a color

A

A form of synesthesia

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83
Q

Is it uncommon for patients with visual loss to experience visual hallucination (phantom vision)

A

No, it is common

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84
Q

Complex visual hallucinations that often take the form of a person, but are recognized as the patient as not being real, occur in what syndrome

A

Charles bonnet syndrome

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85
Q

Area of the brain that plays a big role in encoding memories

A

Hippocampus

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86
Q

Is there evidence that neurons with highly specialized receptive fields may play a role in encoding memories

A

Yes

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87
Q

Perceptual learning has been used to improve what 2 things

A
  • visual function in amblyopia

- near VA in children with low vision

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88
Q

The cortex manifests a significant degree of what

A

Specialization

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89
Q

Brain areas involved in ventral processing stream

A

V4 and IT

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90
Q

Brain areas involved in dorsal stream

A

MT/V5

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91
Q

What part of the brain may coordinate integration of info from the 2 systems

A

Prefrontal cortex

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92
Q

Neurons in what part of the brain correspond closely with our perceptions and playa role in perceptual learning, striate cortex or higher visual centers?

A

Higher visual centers

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93
Q

What picture can be used to possibly train vision

A

Necker cube

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94
Q

Stimulus for: EOG

A

Adaptation

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95
Q

Stimulus for: ffERG(flash)

A

Ganzfield flash

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96
Q

Stimulus for: ffERG(flicker)

A

Ganzfield flash

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97
Q

Stimulus for: pERG

A

Pattern reversal

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98
Q

Stimulus for: mfERG

A

Multifocal flash pattern

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99
Q

Stimulus for: VEP

A

Pattern reversal

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100
Q

Stimulus for: mfVEP

A

Multifocal pattern reversal

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101
Q

Magnitude of: EOG

A

6 mV

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102
Q

Magnitude of: ffERG (flash)

A

1 mV

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103
Q

Magnitude of: ffERG (flicker)

A

1 mV

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104
Q

Magnitude of: pERG

A

5 microV

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105
Q

Magnitude of: mfERG

A

1 microV

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106
Q

Magnitude of: VEP

A

5 microV

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107
Q

Magnitude of: mfVEP

A

1 microV

108
Q

Tissue evaluated with: EOG

A

RPE

109
Q

Tissue evaluated with: ffERG (flash)

A
  • PR
  • Bipolar/Mueller
  • GC
110
Q

Tissue evaluated with: ffERG (flicker)

A

Cone

111
Q

Tissue evaluated with: pERG

A

GC

112
Q

Tissue evaluated with: mfERG

A

Macular function

113
Q

Tissue evaluated with: VEP

A

Visual cortex

114
Q

Tissue evaluated with: mfVEP

A

Focal visual cortex

115
Q

Components of: EOG

A

Arden ratio

116
Q

Components of: ffERG (flash)

A
  • a wave
  • b wave
  • oscillatory pot
117
Q

Components of: ffERG (flicker)

A

Amplitude - phase

118
Q

Components of: pERG

A

Amplitude and phase

119
Q

Components of: mfERG

A

Focal macular function

120
Q

Components of: VEP

A

P-100 Amp/Lat

121
Q

Components of: mfVEP

A

Focal cortical function

122
Q

Do you signal average: EOG

A

No

123
Q

Do you signal average: ffERG(flash)

A

No

124
Q

Do you signal average: ffERG (flicker)

A

No

125
Q

Do you signal average: pERG

A

Yes

126
Q

Do you signal average: mfERG

A

Yes

127
Q

Do you signal average: VEP

A

Yes

128
Q

Do you signal average: mfVEP

A

Yes

129
Q

With EOG, is there a lower dipole voltage under dark or light adapted conditions

A

Dark adapted

130
Q

One condition in which the ERG is normal, but the EOG is abnormal is

A

Best’s autosomal Dominant Vitteliform Maculopathy (fired egg appearance)

131
Q

The a wave of the ERG is from what cells

A

PR

132
Q

The b wave of the ERG is from what cells

A

Bipolar layer and the depolarization of the mueller cells

133
Q

The oscillatory potentials of the ERG is from what cells

A

Ringing in neural transmission at amacrine layer

134
Q

The c wave of the ERG is from what cells

A

RPE

135
Q

Are ffERG’s useful for maculopathies

A

No bc only a small part of the retinal is affected

136
Q

Stimulus used in scotopic ERG

A

Dim blue stimulus to limit response to rods only

137
Q

What flicker is used in the photopic ERG

A

30 Hz

138
Q

What does a 60 Hz ERG look like

A

Flat because you have reach the CFF

139
Q

Which looks best at problems like retinitis pigmentosa that affect entire classes of cells

A

ff-ERG

140
Q

Is ffERG good for focal lesions, such as maculopathy

A

No

141
Q

Which 2 tests use a steady state alternating phase checkerboard or grating stimulus

A

VEP and pERG

142
Q

Do you signal average pERG and VEP

A

Yes, due to the low voltage outputs

143
Q

Area of most organized primary visual reception in cortex

A

Visual cortex area 17

144
Q

Measures macular/foveal function

A

VEP

145
Q

VEP: If there is a decrease in amplitude and a delayed response in an eye, suspect

A

Amblyopia

146
Q

VEP: If there is an extreme delay in response, suspect

A

MS

147
Q

Which test will require best, precise fixation

A

Mf-ERG

148
Q

Do you signal average mf-ERG

A

Yes

149
Q

Presents local luminance shifts (flashes)

A

Mf-ERG

150
Q

Long term chloroquine toxicity can cause what

A

Central vision loss -> bulls eye maculopathy

151
Q

What cells give rise to most of large positive going potential seen in b wave of ff-ERG(flash)

A

Mueller cells

152
Q

30 yo pt with 20/20OD and 20/80OS has normal ffERG, mild amplitude reduction and a latentncy delay in high spatial frequency VEP, occurring only on OS. Suspect?

A

Amblyopia

153
Q

Pt is on hydroxychloroquine; 65 yo and has been on it many years. Which study proved most useful to VFs and OCT in diagnosis of this pt?

A

Mf-ERG

154
Q

Frequency characterized by nearly extinguished ffERG

A

Retinitis pigmentosa

155
Q

35 you with longstanding VA loss bilaterally getting worse. Just noticeable granular pigment in macula. No issue with night vision. Vague family Hx of going blind at young age. Suspect cone dystrophy. What tests would provide useful info supporting diagnosis: ffERG(flicker), dark adapted ffERG, pERG

A

All

  • ffERG(flicker): bc it uses cones
  • dark adapted ffERG: to see if it is only cones or if rods are involved
  • pERG: primary cones bc looking at retinal response to acuity
156
Q

A subject view two patches of light. 1 patch consists of an additive mixture of 475 and 510nm and the other was a mixture of 490 and 520nm. By adjusting the intensities of each of the wavelengths that constitute these patches, the subject is ale to perfectly match the 2 patches. The subject’s vision:

A

Could be either monochromatic, dichromatic, or trichromatic

157
Q

What cone photopigment evolved most recently

A

Chlorolabe

158
Q

3 perceptual dimensions of color

A

Hue
Brightness
Saturation

159
Q

Does a person with monochromatic have color discrimination?

A

No, they only have 1 cone photopigment

160
Q

What is the only way to differentiate color is pt is monochromatic

A

If the quantal absorption’s are different

161
Q

In a dichromatic patient, if they are unable to match two patches of different wavelengths of light, does the pt possess the ability to make discriminations based purely on wavelength?

A

Yes

- if they can match them, they do not have the ability to make wavelength based discrimination

162
Q

2 stimuli that appear identical, it are physically different

A

Metamers

163
Q

Most humans have what kind of vision

A

Trichromatic

164
Q

What part of the cone photopigment is identical for all

A

Chromophore

165
Q

What part of the cone photopigment is the visually inert chain of amino acids

A

Opsin

166
Q

the M and L cone opsin genes are found on what chromosome

A

X

167
Q

Where is the s cone photopigment gene located

A

Chromosome 7

168
Q

Where is the rhodopsin gene found

A

Chromosome 3

169
Q

Are M and L cone opsin genes similar or different

A

Very similar

- 98% homologous

170
Q

A stimulus of 540 nm has a hue of

A

Green

171
Q

A stimulus of 570 nm has a hue of

A

Yellow

172
Q

3 wavelengths that do not change hue as their intensity is increased

A

Blue-478
Green-503
Yellow-578

173
Q

Stimuli with wavelengths shorter than 503 appear

A

Blue as intensity increases

174
Q

Stimuli longer than 503 appear

A

Yellow as intensity is increased

175
Q

Appears as a pastel

A

Desaturated color

176
Q

Does a monochromatic stimulus of 570nm appear more or less saturated than a monochromatic stimulus of any other wavelength

A

Less saturated

177
Q

Which wavelengths have the best discrimination

A

495 and 590nm

178
Q

The approximately constant color appearance of objects as lighting conditions change

A

Color constancy

179
Q

What is processed by bipolar hue channels

A

Color

180
Q

What are the 2 bipolar hue channels

A

Red-green

Blue-yellow

181
Q

In the red-green or blue-yellow channel, are colors signaled individually or simultaneously

A

Individually

182
Q

What is coded by a white-black channel

A

Brightness

183
Q

A wavelength below 570 causes

A

Inhibition

184
Q

A wavelength above 570 causes

A

Excitation

185
Q

Spectral sensitivity function for a typical non color opponent neuron peaks at

A

555nm

186
Q

Postreceptoral antagonism first occurs where

A

Bipolar cells

187
Q

Color vision is normally

A

Trichromatic

188
Q

What plays a critical role in coding color info

A

Opponent processing

189
Q

What type of neurons are in the LGN

A

Color opponent

190
Q

L and M cones _______ eachother

A

Oppose

191
Q

__ cones are opposed by an addition of L and M

A

S cones

192
Q

Non color opponent cells sum the input of

A

L and M

193
Q

Wiring diagrams give the connections of what cells

A

Cones, horizontal cells and bipolar cells

194
Q

For foveal red-green cells, what contributes to the excitatory center

A

A single L cone

195
Q

For foveal red-green cells, what contributes to the inhibitory surround

A

Many m cones

196
Q

For blue-yellow cells, what contributes to the excitatory center

A

S cones

197
Q

For blue-yellow cells, what contributes to the inhibitory surround

A

L and M cones

198
Q

An achromatic cell has what input to both the excitatory center and inhibitory surround

A

L and M to both

- makes cell monochromatic

199
Q

Cells that manifest red-green opponency

A

Parvo

200
Q

Cells that manifest yellow-blue opponency

A

Konio

201
Q

Cells that are non-color opponent

A

Magno

202
Q

Most distal color opponent neurons

A

Bipolar

203
Q

Hue info is encoded by

A

Color opponent neurons

204
Q

Allows us to precisely specify any possible color

A

CIE color system

205
Q

The quantity of each primary required for a match is referred to as what

A

Tristimulus value

206
Q

For wavelengths from 450 to 525, what is required to obtain a match

A

Negative amounts of lamdaR are required

207
Q

With the CIE diagram, how do you find coordinate Z

A

1- (X + Y)

So: X + Y + Z = 1

208
Q

How to find excitation purity

A

A/(A+B)

A: from W to the line
B: from line to end of diagram

209
Q

A mixture of 3 parts 580 and 1 part 490; which side of the diagram will it intersect closer to

A

Closer to 580 (3/4 of the way there)

  • connect line from white to edge of diagram to find the dominant wavelength of the mixture
  • then use a and b to find excitation purity
210
Q

Complementary colors when mixed together produce

A

White

211
Q

How to find a complement wavelength from the CIE diagram

A

Go from the given wavelength through W to opp side of diagram

212
Q

Specifies the relative amounts of primaries necessary to match a color sample

A

CIE diagram

213
Q

Do CIE primaries physically exist

A

No, they are imaginary

214
Q

Why does the CIE primaries use imaginary primaries

A

To avoid use of negative quantities

215
Q

What percent of the population manifest anomalous color vision

A

4.5

216
Q

Are most color vision anomalies inherited or acquired

A

Inherited

217
Q

Which kind of color vision anomalies are non progressive and pose no threat

A

Inherited

218
Q

What kind of color vision anomalies are secondary to disease or drug toxicity

A

Acquired

219
Q

Missing 1 of the 3 cone photopigment

A

Dichromacy

220
Q

When chlorolabe is missing

A

Deuteranopia

221
Q

When erythrolabe is missing

A

Protanopoia

222
Q

When cyanolabe is missing

A

Tritanopia

223
Q

In deuteranopia, what is chlorolabe replaced with

A

Erythrolabe

224
Q

In protanopia, what is erythrolabe is replaced by what

A

Chlorolabe

225
Q

3 photopigments are present but absorption spectrum of 1 is displaced

A

Anomalous trichromacy

226
Q

Chlorolabe is displaced toward longer wavelengths

A

Deuteranomalous trichormacy

227
Q

Erythrolabe spectrium is displaced toward shorter wavelengths

A

Protanomalous trichromacy

228
Q

People with protan and deutan usually confuse what colors

A

Reds and greens

229
Q

People with Tritan vision confuse what colors

A

Blues and yellows

230
Q

4 characteristics that distinguish anomalous color vision

A

Spectral sensitivity
Wavelength discrimination
Color confusion lines
Perception of saturation

231
Q

The luminance V(lamda) function normally peaks at about

A

555nm

232
Q

Protanopic V(lamda) curve shows what

A

BIG displacement toward shorter wavelengths

233
Q

Deuteronopic v(lamda) function shows what

A

SLIGHT displacement toward longer

234
Q

The greater dislocation of the protanopic luminance function suggest that which cones play a greater role in generating the normal v(lamda)function

A

L cones

235
Q

Protanopoia have difficulty seeing what color

A

Red

236
Q

Luminosity functions in anomalous trichromacy

A

Same general dislocation as dichromatic functions, but less pronounced

237
Q

Protanopia and deuteranopia have well developed wavelength discrimination at what wavelength

A

490nm

238
Q

There is no ability for people with protanopia and deuteranopia to discriminate at what wavelengths

A

545 and beyond

239
Q

In pts with deuteranopia and protanopia, the only way they can discriminate among longer than 545 nm is by

A

Difference in luminance

240
Q

All colors falling along confusion line are

A

Indistinguishable

241
Q

Are all spectral stimuli equally saturated

A

No

242
Q

In normal trichromacy, what wavelength appears less saturated (more whitish)

A

570

243
Q

Deuteranopia function intersects the abscissa at (neural point)

A

498nm

244
Q

Protanopic function intersects the abscissa at (neutral point)

A

492 nm

245
Q

The neutral point in tritanopia is

A

569nm

246
Q

Do people with normal color vision and anomalous trichromacy manifest neutral points

A

No

247
Q

Wavelength discrimination is best in the region of

A

The neutral point

248
Q

The most commonly inherited anomaly is

A

Anomalous trichromacy

249
Q

The boy always receives the defective CV gene from which parent

A

Mother

250
Q

Hereditary or acquired: symmetric

A

Hereditary

251
Q

Hereditary or acquired: stable

A

Hereditary

252
Q

Hereditary or acquired: no cause

A

Hereditary

253
Q

Hereditary or acquired: asymmetric

A

Acquired

254
Q

Hereditary or acquired: recent history of color naming errors

A

Acquired

255
Q

Hereditary or acquired: unstable

A

Acquired

256
Q

Hereditary or acquired: caused by disease or toxicity

A

Acquired

257
Q

Changes in transmission propertiesof lens secondary to aging result in what color vision anomaly
- this is known as what rule

A
  • blue yellow anomalies

- Kollner’s rule

258
Q

Outer retinal disease result in what CV anomalies

A

Blue yellow

259
Q

Disease of the inner retina, ON, visual paths and visual cortex result in

A

Red green anomalies

260
Q

Rare conditions where the pt manifests monochromatic vision

A

Achromatopsias

261
Q

What color lenses minimize the bleaching of rhodopsin and may be recommended for pts with achromatopsias

A

Dark red lenses

262
Q

Distortion of color

A

Chromatopsias

263
Q

Digitalis and fluorescein may produce

A

Xanthopsia (yellow vision)

264
Q

Most commonly used CV tests

A

Pseudoisochromatic plate tests

265
Q

Do pseudoisochromatic plate tests distinguish dichromatic and anomalous trichormatic

A

No

266
Q

Appearance of 546 stimulus in angel anomaloscope

A

Bright

267
Q

Appearance of 670 stimulus in angel anomaloscope

A

Dim