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2nd year drugs > block 10 > Flashcards

block 10 Flashcards

1
Q

ACE inhibitor examples

A

Enalapril, Lisinopril, Ramipril, and Captopril

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2
Q

what does ACE produce

A

andiotensin 2

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3
Q

what does angiotensin 2 do

A

increases blood pressure

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4
Q

4 ways angiotensin 2 affects blood pressure

A

aldosterone from adrenal cortex
vasoconstriction
vasopression from posterior pituitary
thirst increases

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5
Q

sodium channel blocker

A

amiloride

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6
Q

action of amiloride

A

potassium sparing

antihypertensive

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7
Q

where does amiloride work

A

collecting ducts

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8
Q

loop diuretic

A

furosemide

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9
Q

what do loop diuretics do

A

inhibit sodium potassium chloride channels

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10
Q

where does furosemide work

A

loop of henle

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11
Q

thiazide diuretics

A

Bendroflumethiazide

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12
Q

bendroflumethiazide and chlorlitone are

A

Sodium chloride cotransporter inhibitor

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13
Q

monosulfonamly diuretic

A

chlorlitone

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14
Q

Alpha adrenoreceptor antagonist

A

doxazosin

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15
Q

doxazosin treats

A

hypertension

and benign prostatic hyperplasia

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16
Q

potassium sparing diuretic

A

spirolactone

17
Q

spirolactone

A

Mineralocorticoid nuclear hormone receptor antagonist

18
Q

how does spiralactone work

A

competing for intracellular aldosterone receptor in the distal convoluted tubule cells

19
Q

crabonic anhydrase inhibitor

A

Acetazolamide

20
Q

how does aceazolamide work

A

reduces the amount of hydrogen ions for sodium movement

increased excretion of sodium and water

21
Q

DNA cross linker

A

cisplatin

22
Q

cisplatin is used to treat

A

cancer

23
Q

folate antagonist

A

methatrexate

24
Q

how does methatrexate work

A

stops the production of tetrahydrofolic acid and therefor stops production of pyrimadines and purines

25
Q

what can methatrexate be used for

A

RA

26
Q

GABA receptor agonist

A

Phenobarbital

27
Q

phenobarbital is used for

A

anticonvulsant

28
Q

opiate receptor agonist

A

pethidine

29
Q

pethidine is used for

A

pain

30
Q

osmotic diuretic

A

mannitol

31
Q

noradrenalin, serotonin and dopamine releaser

A

amphetamine

32
Q

vitamin K antagonist

A

warfarin

33
Q

what is warfarin used as

A

anticoagulant

34
Q

warfarin is used in

A

thrombosis
thromboembolism
pulmonary embolism
ischemic stroke with atrial fibrillation

2nd year drugs (2 decks)

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