Block 1 Part 2

Question 1

Source of the CNS

Answer 1

Ectoderm

Question 2

what is CNS development controlled by

Answer 2

mesoderm signals, growth factors, adhesion molecules

Question 3

notochord in adults is

Answer 3

nucleus pulposus of intervertebral disks

Question 4

functions of the notochord

Answer 4

defines longitudinal axis, determines orientation of vertebral column, directs ectoderm to form the neural plate

Question 5

what is SHH responsible for

Answer 5

differentiation of the dorsal surface of the CNS

Question 6

what is Wnt responsible for

Answer 6

differentiation of the ventral surface

Question 7

what does neural plate become

Answer 7

the neural tube

Question 8

colchicine

Answer 8

depolymerizes microtubules

Question 9

cytochalasin

Answer 9

inhibits microfilament-based contraction

Question 10

dysraphic defects

Answer 10

congenital malformations from defective neurulation