Block 1 - Anatomy - Thorax - Gray's Review Flashcards
A 2-day-old newborn is diagnosed with transposition of the great arteries. Which structure is primarily responsible for the division of the truncus arteriosus into the great arteries?
A. Septum secundum
B. Septum primum
C. Bulbar septum
D. Aorticopulmonary septum
E. Endocardial cushions
D. Aorticopulmonary septum
What defect accounts for 25% of all congenital heart defects?
Ventricular septal defect
(most commonly membranous)
What heart defect can keep a child with transposition of the great arteries alive until the transposition is corrected?
A patent ductus arteriosus
(to allow mixing of oxygenated and unoxygenated blood)
A 32-year-old woman in her third trimester of pregnancy is undergoing a routine ultrasound examination.
The examination of the fetus reveals enlarged and echogenic lungs, an inverted diaphragm, and fetal ascites. Which condition is best characterized by these signs?
A. Laryngeal atresia
B. Tracheal atresia
C. Polyhydramnios
D. Lung hypoplasia
E. Oligohydramnios
A. Laryngeal atresia
Ultrasound examination of a fetus with laryngeal atresia might show what signs?
Enlarged and echogenic lungs, an inverted diaphragm, fetal ascites
A child presents with a loud S1 and a wide, fixed-split S2. What is the likely diagnosis?
Atrial septal defect
What heart murmur indicates an atrial septal defect?
A loud S1 and a wide, fixed-split S2
For what type of heart defects are children with Down syndrome especially at risk?
Atrial and ventricular septal defects
(endocardial cushion defects)
(especially septum-primum atrial defects)
Tetralogy of Fallot and truncus arteriosus are both associated with what genetic predisposition?
22q11 deletions
What heart defects are associated with 22q11 deletions?
Tetralogy of Fallot and truncus arteriosus
Which pharyngeal arches lead to the development of the portions of the aorta that may become congenitally coarcted?
The 3rd, 4th, and 6th arches
What primordial structure must fail to develop in order for a tracheoesophageal fistula to form?
The tracheoesophageal septum
What type of atrial septal defect can occur along the junction with the superior vena cava?
A sinus venosus ASD
Where can sinus venosus atrial septal defects be found?
Close to the entry of the superior vena cava
Failure of fusion of the lateral folds during development can lead to what congenital heart defect?
Ectopia cordis
(the heart is located outside the chest wall)
What is ectopia cordis?
A congenital defect in which the heart is located outside the body cavity.
(due to failure of the lateral folds to fuse during development)
A newborn baby is diagnosed with eventration of the diaphragm. In this condition, half of the diaphragm ascends into the thorax during inspiration, while the other half contracts normally. What is the cause of this condition?
A. Absence of a pleuropericardial fold
B. Absence of musculature in one half of the diaphragm
C. Failure of migration of diaphragm
D. Failure of the septum transversum to develop
E. Absence of a pleuroperitoneal fold
B. Absence of musculature in one half of the diaphragm
What structure, in particular, should a surgeon be careful not to disrupt in closing a ventricular septal defect?
The right bundle branch
If a patient with retrosternal chest pain (that radiates to the left arm) can relieve some of the pain by leaning forward, what would that indicate?
This is a pericardial friction rub, likely due to pericarditis
What three nerves are most at risk for damage during a mastectomy?
The long thoracic nerve, the intercostobrachial nerve, and the thoracodorsal nerve.
The intermediolateral horns of the spinal cord at levels T5 - T9 contain cell bodies for neurons innervating what region of the body?
To what kind of nerves do these cell bodies belong?
Abdominal organs;
sympathetic preganglionic nerves
The intermediolateral horns of the spinal cord at levels T1 - T4 contain cell bodies for neurons innervating what region of the body?
To what kind of nerves do these cell bodies belong?
The upper limbs and thoracic cavity;
sympathetic preganglionic nerves
What nerve carries the cardiac sympathetic efferent fibers from the sympathetic ganglia to the thoracic viscera and visceral afferent fibers for pain from these organs?
The cardiopulmonary splanchic nerves
For what is the cardiopulmonary splanchnic nerve responsible?
The cardiac sympathetic efferent fibers;
the visceral afferent fibers for the thoracic organs















