Blepharitis

Question 1

Blepharitis Definition

Answer 1

eyelid margin infection

Question 2

Blepharitis Causes

Answer 2

Bacterial infection
Inflammation/hypersecretion of the sebaceous glands
Meibomian gland dysfunction

Question 3

Blepharitis Pathophysiology

Answer 3

Staph aureus, Staph epidermidis
Mite infestation
Antigen-induced or inflammatory reaction

Question 4

Blepharitis Manifestations

Answer 4

Thickening of the eyelid margin
Plugging of the meibomian glands

Question 5

Blepharitis Diagnostic Criteria

Answer 5

Based on symptoms
Irritated red eyes and burning sensation
Increases in tearing, blinking, photophobia,
Eyelid sticking and contact lens intolerance.

Question 6

Blepharitis Treatment

Answer 6

Strict eyelid hygiene and warm compresses
Eradicate the pathogen

Question 7

Blepharitis Treatment-non-pharmacological

Answer 7

Scrubbing the eyelashes with gentle, no-tears shampoo
Warm compresses
No contact lens use during treatment period
Discard eye make up to prevent reinfection

Question 8

Blepharitis First line -> abx

Answer 8

Erythromycin 0.5% ophthalmic ointment (eyelid margin) or
Bacitracin 500 units/g ointment or
An ophthalmic fluoroquinolone solution (besifloxacin, gatifloxacin, levofloxacin, or moxifloxacin)

Question 9

Drug Therapy for Blepharitis

Answer 9

(Basically mycins and floxacins)
Sulfacetamide sodium 10% solution (Bleph-10)
Bacitracin 500 units/g ointment
Erythromycin 0.5% ointment
Gentamicin 0.3% solution or ointment (Gentak)
Tobramycin 0.3% solution or ointment (Tobrex)
Besifloxacin 0.6% suspension (Besivance)
Ciprofloxacin 0.3% solution or ointment (Ciloxan)
Gatifloxacin 0.3% solution (Zymaxid)
Levofloxacin 0.5% solution (Quixin)
Moxifloxacin 0.5% solution (Moxeza, Vigamox)
Ofloxacin 0.3% solution (Ocuflox)
**Polymyxin B sulfate, trimethoprim sulfate solution (Polytrim) -combination