Bleeding Flashcards

1
Q

What i the definition of shock

A

A clinical syndrome where tissue perfusion and oxygenation is inadequate to maintain normal metabolic function

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2
Q

Describe hypovolaemic shock

A

Shock which involves a haemohhrage. Involves a burn/sweat

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3
Q

Describe cardiogenic shock

A

Heart pump fails

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4
Q

Describe septic shock

A

Fluid distribution

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5
Q

Describe spinal shock

A

Loss of vascular tone

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6
Q

Describe anaphylactic shock

A

A combination of 2 or more different types of shock

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7
Q

How would you give emergency treatment to someone in shock?? ABCDE

A
Airway control with c spine control
Breathing with oxygenation
Circulation with haemorrhage control
Disability
Exposure
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8
Q

Define haemostasis

A

The stopping of the flow of blood

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9
Q

WHat 2 pathways are involved?

A

Extrinsic and instrinsic

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10
Q

What triggers the extrinsic pathway?

A

Damaged tissues - trauma to tissues

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11
Q

What triggers the intrinsic pathway?

A

Activated platelets - trauma to actual blood itself

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12
Q

What occurs before the intrinsic/extrinsic pathways?

A

Vascular system

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13
Q

Describe the vascular system

A

Endothelial cells stop secreting coagulationand aggregation inhibitiors and secrete von willebrand facotr. VWF binds to factor 8, causing platelet adherance during initial clotting

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14
Q

Describe the extrinsic pathway

A

Factor 12 activates factor 10 and prothrombin.

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15
Q

Describe the intrinsic pathway

A

Factor 12 is activated by collagen, which leads to the activation of factor 8 9 10 11 and prothrombin

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16
Q

Describe the final common pathway of haemostasis

A

Factor XA converts prothrombin to thrombin. Thrombin converts fibrinogen to fibrin. Factor 8 cross links the thrombin polymer to consolidate the thymus

17
Q

What regulates haemostasis and prevents blood clotting?

A

Thrombomodulin which bind to thrombin to prevent coagulation and activates protein C which inactivates cofactor VA and VIIIa

18
Q

Where iss EPO produced

A

kidney

19
Q

What do platelets adhere to when a vessel is damaged?

A

Exposed collagen on the damaged vessel wall

20
Q

Name an anticoagulant preservative

A

sodium citrate