Bladder CA

Question 1

Which lymph node is common in bladder CA metastasis?

Answer 1

• Internal iliac nodes
• Para-aortic lymph nodes

Question 2

How would you manage a case of superficial (Non-muscle invasive) bladder CA (pTa, pT1)?

Answer 2

1. Transurethral resection of the bladder tumor (TURBT) and send tissue for HPE

TURBT -> Diagnostic, therapeutic and staging modality
2. Intravesical chemotherapy (MITOMYCIN C, DOXORUBICIN) -> This can reduce the recurrence of the disease
3. Regular follow-up for cystoscopic examination

Question 3

How would you manage a case of muscle-invasive bladder CA (pT2, pT3)?

Answer 3

1. Non-adjuvant systemic chemotherapy (CISPLATIN, METHOTREXATE, DOXORUBICIN and VINBLASTINE)
2. Radical cystectomy and pelvic lymphadenopathy (pT2 - pT3) -> Ileal conduit diversion
3. External beam radiotherapy (4-6 weeks)

Question 4

What staging system is used in bladder CA?

Answer 4

UICC SYSTEM
Union for international cancer control