BL S5 - Epithelial TIssue And Exocrine Glands Flashcards

1
Q

What does a mucous membrane do?

Give examples of where mucous membranes are found.

A

Lines internal tubes which open to the exterior of the body.

The respiratory, urinary and alimentary tract.

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2
Q

What does a mucous membrane consist of?

A

Epithelium lining a lumen
Adjacent layers of CT called lamina propria.
Muscularis mucosae - smooth muscle - alimentary tract.

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3
Q

What is a serous membrane and where are they found?

A

Thin 2 part membranes which line internal closed body cavities - enveloping viscera.

Peritoneum - enveloped abdominal organs
Pleural sacs - envelop lungs
Pericardial sacs - envelops heart

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4
Q

What does a serous membrane consist of?

A

Mesothelium - secretes the lubricating fluid

Thin layer of connective tissue attached the epithelium to adjacent tissues.

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5
Q

What is epithelium tissue?

Where us is found?

A

Sheets of contiguous cells, of varied embryonic origin that cover the external surface of the body and line the internal surfaces.

Skin
GI tract, respiratory, genitourinary tract. - open to exterior
Pericardium, peritoneum, pleural sacs, blood and lymphatic vessels - don’t open to exterior.

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6
Q

What is the function of simple squamous epithelium?

A

Lubrication
Gas exchange - short diff distance
Physical barrier
Active transport via pinocytosis

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7
Q

Where is simple squamous found?

A

Bowmans capsule
Lung alveoli
Endothelium
Mesothelium

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8
Q

What happens if excessive secretion of fluid occurs from squamous cells?

A

Hydroceles around testes

Serous fluid between visceral andparietal layers of the tunica vaginalis

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9
Q

Describe simple cuboidal epithelium.

A

Single layer of polygonal cells where their height is the same as their width.

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10
Q

What are the functions of simple cuboidal and where are they found associated with the function?

A

Absorption / conduit - exocrine glands
Absorption and secretion - kidney tubules
Barrier - ovary
Hormone synthesis, storage and mobilisation - thyroid

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11
Q

Describe simple columnar epithelium.

A

Single layer of cells with heights greater than their wights.

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12
Q

What are the functions of simple columnar and where are the Found associated with these functions?

A

Absorption - small intestine, colon and gall bladder.
Secretion - stomach lining, small intestine and colon
Lubrication - small intestine and colon
Transport - oviduct.

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13
Q

Describe psuedostratified epithelium.

A

All cells make contact with the basement membrane but not all reach surface - nuclei at varying levels. Often ciliated.

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14
Q

What are the functions of pseudostratified epithelium and where are they found?

A

Secretion and conduit - respiratory tract, vas deferens
Mucous secretion - respiratory tract
Particle trapping and removal - respiratory tract

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15
Q

Describe stratified squamous epithelium.

A

Multiple layers with the outermost being squamous cells.

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16
Q

Where is non-keratinised stratified squamous epithelium found?

A
Anal canal
Cornea
Oral cavity 
Oesophagus 
Valine
Inner surface of the eye
17
Q

What is the fucntion of non-keratinised epithelium?

A

Protect against abrasion

Reduce water loss but remain moist

18
Q

What are the functions of keratinised epithelium?

A
Reduces water loss and ingress
Prevents toxin ingress
Protects against abrasion 
Acidic pH - reduces microbial colonisation
Shielding against UV damage.
19
Q

Where is keratinised epithelium mainly Found?

A

Skin epidermis

20
Q

Describe transitional epithelium.

A

Surface cells vary in shape from columnar to cuboidal depending on where the tissue is stretch or relaxed.

21
Q

Where is transitional epithelium aka urothelium found?

A
Urinary tract
Renal calyces 
Ureter
Bladder
Urethra
22
Q

What are the functions of transitional epithelium?

A

Distensibility

Protection of underlying tissue from toxic chemicals

23
Q

What percentage of the epidermis is keratinocytes?

24
Q

What are the 4 layers of the epidermis?

A

Stratum corneum
Stratum granulosum
Stratum spinosum
Stratum basale

25
Where does keratinocytes mitosis occur?
Basal layer.
26
What does keratin form?
Hair and nails
27
What is normal transit time from basal layer to corneum?
28-40 days
28
What is different about normal transit time and transit time of keratinocytes from the basal to corneum layer in diseases such as psoriasis? What are symptoms?
Decreased transit time Silvery scales and redness in affected area.
29
What are some other epidermal cells?
Melanocytes | Langerhans cells
30
What are functions of melanocytes?
Produce melanin - transferred to other epidermal cells via phagocytosis of the melanosomes contained in the dendritic processes of the melanocytes.
31
What is the function of langerhans cells?
Pro APCs Present antigens to T lymphocytes Mediate immune reactions such as contact dermatitis
32
What is a gland?
A gland is an epithelial cell or collection of cells specialised for secretion.
33
What is an adenocarcinoma?
Malignant growth derived from glandular tissue or epithelial origin.
34
What are some ways glands can be classified?
Multi or unicellular Tubular or acinar Exocrine or endocrine
35
Give 2 examples of unicellular glands.
Goblet cells. | Crypts of lieuberkuhns
36
What is an acinus?
A small sac like cavity surrounded by secretory cells.