Bk 1 Ch 4 Inheritance Flashcards
Model organisms
Species that for a number of reasons I found favour in research laboratories
Eg. E.coli S.cerevisiae C.elegans A. thaliana D. melanogaster M. musculus
Eukaryotic Genome
Nuclear DNA in ch 4
Can be applied more widely to include DNA all organelles.
Human has 23 chromosome pairs one pair of these are sex chromosomes. What are the non-sex chromosomes known as?
Autosomes.
Homologous chromosomes
Pairs of autosomes, of equal length which carry an equivalent set of genes.
What is the pair of sex chromosomes which differ in males and females known as?
Heterosomes
Karyotype
The characteristic number and appearance of chromosomes in the nucleus of the cell from a particular species
In prophase 1 of meiosis when the homologous chromosomes are actually physically paired together what is the process known as?
Synapsis
What is the phenotype ratio characteristic of a heterozygous cross involving two genes located on different chromosomes that assort independently?
9:3:3:1
Recombinant
In genetics, a cell or an individual with a new combination of gene alleles not found in either parent, usually applied to linked genes (on the same chromosome). In gene cloning, the product of inserting a DNA fragment from one organism into the DNA molecule of another. The resultant recombinant DNA molecule is a combination of the two.
When given a table with number of plants from an F1 generation cross with a recessive homozygote how can you tell which of the Genotypes are recombinants?
The recombinant gametes occur at a much lower frequency than the non-recombinants
Recombination frequency
Can be worked out from the percentage of different phenotypes at which recombination has occurred between the 2 gene loci
=( (a +b)/ total plants) x100%
How to read a pedigree
For condition Try:
1 hypothesis Dominant asomatic gene
2 hypothesis Recessive asomatic gene
3 hypothesis Sex linked
Look at parents and offspring (use punnet square)
Mitochondrial pedigree
Gene inherited from female
Check offspring
Pure breeding plants
Those which when self crossed always yield progeny of the same phenotype as the parental plants
Linkage
Where two genes are located on the same chromosome and are unable to assort independently during a genetic cross.