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Phto > Bitter Principles > Flashcards

Bitter Principles Flashcards

1
Q

Uncetain chemicals of bitter principles?

A

Picrotoxin, colocynthin, quassin

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2
Q

Abundant bitter principles?
Compositae?
Labiatae?
Gentianaceae?

A

All of them

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3
Q

Phenolic bitter principles family?
Rutaceae or cannabinaceae?

A

Cannabinaceae

Humulus lupulus cannabinaceae

Humulone + lupulone

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4
Q

What is used in the preparation of beer? Belongs to which bitter principle

A

Hops, Phenolic bitter principle

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5
Q

Alcoholic soln. Humulone + Fecl3 —> ??

A

Reddish violet

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6
Q

Santonin belongs to lactone or coumarin bitter principles?
Its family?

A

Lactone

Compositae

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7
Q

% of santonin and artemisin

A

2-3.5% of santonin and artemisin

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8
Q

Santonin + NaOH —> ??

A

Violet red changes to reddish yellow

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9
Q

Santonin + ?? + h2o —> no colour , + fecl3 —> violet

A

H2so4

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10
Q

Khellin is a chromone bitter principle, its S.N?

A

Ammi Visnaga Umbellifera

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11
Q

Ammi visnaga umbellifera refers to chromone or coumarone?

A

Chromone

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12
Q

Khellin + ?? —> rose red

A

KOH

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13
Q

Khellin + tannic acid. —> ??

A

Faint ppt.

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14
Q

Uses: coronary vasodilator + bronchodilator

Bitter principle ?S.N ?

A

Chromone, ammi visnaga

Khellin

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15
Q

Xanthotoxin (ammoidin) is coumarone or coumarin?

A

Coumarin

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16
Q

Ammi majus (family?)
Ruta gravelolens (family?)
Fragara xanthoxyloides (family?)

Coumarone or coumarin?

A

Umbelliferae
Rotaceae
Umbelliferae

Coumarins of xanthotoxin

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17
Q

Xanthotoxin + h2so4 —>
Xanthotoxin + froehd’s reagemt —>

A

Orange yellow

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18
Q

Which reagent gives orange yellow —> light green when reacting with xanthotoxin?

A

H2SO4

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19
Q

Which reagent gives orange yellow —> dirty green when reacting with xanthotoxin?

A

Froehd’s reagent

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20
Q

Used for leukodermia?

A

Xanthotoxin (ammoidin) , coumarin bitter principle

Ammi majus umbelliferae
Fragara xanthoxyloides umbelliferae

Ruta gravelolens rutaceae

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21
Q

Coumarone bitter principles ? Xanthotoxin - khellin - rotenone?

A

Rotenone

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22
Q

Derris elleptica, derris malacecensis! Lonchocqrpus utilis refer to family? (Liliaceae or leguminosae)?

A

Leguminosae

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23
Q

Preparation pf coumarone, rotenone
Powder + ?? In Soxhlet

A

Ccl4

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24
Q

Preparation pf coumarone, rotenone

Rotenone+ acetone + 50% HNO3 giving what colour ? Red - Blue - violet?

A

Blue

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25
Q

What compound is known as climbing shrub?

A

Picrotoxin
[Anamirta cocculus Menispermaceae]

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26
Q

Menispermaceae belongs to ( picrotoxin or quassin)?

A

Picrotixin

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27
Q

A. Picrotoxin + H2SO4 giving what colour?

B. Pictotoxin + H2SO4 react with what to give blue colour?

C. Picrotixn +?? —> green colour

A

A. Golden yellow turns to reddish brown

B. Anisaldehyde

C. Vanillin hydrochloride

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28
Q

What is used as antidote ( barbiturates poisoning)?

A

Picrotoxin ( anamirta cocculus Menispermaceae)

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29
Q

What is known to be as insecticide and anthelmintic? Picrotixin or quassin?

A

Quassin

Picrotixn: as antidote for barbiturate poisoning

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30
Q

Simaroubaceae for quassin or pyrethrum?

A

Quassin

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31
Q

Quassin+ sucrose + h2so4 —> red or violet?

A

Red

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32
Q

Quassin + phloroglucin + hcl —> violet or crimson colour?

All red colour of quassin test

A

Crimson colour (red)

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33
Q

Sponge Tethya crypta is Ara-A (1) or avarol (4)

A

Ara-A (1)

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34
Q

Is ara-A 1 semi synthetic (yes / No)

A

Yes. Its semi synthetic

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35
Q

Sponge Disidea avarea represents ( Ara-A (1) or Avarol (4) & (5)). ?

A

Avarol (4) & (5)

36
Q

Ara-A (1) and avarol (4) & (5) are:

A. Cytotoxin
B. Antiparasitic
C. Anticoagulant
D. Antiviral

A

D. Antiviral

37
Q

A- kainic acid is :

A. Cytotoxin
B. Antiparasitic
C. Anticoagulant
D. Antiviral
E. Antimicrobial

A

B. Antiparasitic

38
Q

Domic acid is :

A. Cytotoxin
B. Antiparasitic
C. Anticoagulant
D. Antiviral

A

B. Antiparasitic

39
Q

Nereistoxin is:
A. Cytotoxin
B. Agrochemical
C. Anticoagulant
D. Antiviral

A

B. Agrochemical

40
Q

Which one of these compounds represents sea hare:

A. Cytotoxin
B. Antiparasitic
C. Anticoagulant
D. Antiviral

A

A. Cytotoxin

41
Q

Dolastatin represents cytotoxin compound

What is its S.N?

A

Dolabella auricularia

42
Q

Chondria armata represents (a- kainic acid or domic acid) ?
Which group (antiparasitic or anticoagulant)?

A

Domic acid

Antiparasitic

43
Q

Brown algae belongs to :

A. Cytotoxin
B. Antiparasitic
C. Anticoagulant
D. Antiviral

A

C. Anticoagulant

44
Q

Fucoidan is known as ? ( green - red - brown ) algae

Antimicrobial or anticoagulant

A

Brown algae

Anticoagulant

45
Q

Fucus vesiculosus represents ?

A. Cytotoxin
B. Antiparasitic
C. Anticoagulant
D. Antiviral

A

C. Anticoagulant - fucoidan - brown algae

46
Q

Cephalosporin C and cephalothin sodium ( semi- synthetic) ?

A. Cytotoxin
B. Antiparasitic
C. Anticoagulant
D. Antimicrobial

A

D. Antimicrobial

47
Q

Soft coral ( plexaura homomalla ) belongs to:

A. Cytotoxin
B. Prostaglandin
C. Agrochemical
D. Antiviral

A

B. Prostaglandin

48
Q

Nereisoxin S.N?

Hint: Lumb hetero.dopa

A

Lumbriconeris heterpdopa

49
Q

Used as rapid anesthetic on insect, toxic to fish & mammals?

A. Antimicrobial
B. Antiparasitic
C. Agrochemical
D. Antiviral

A

C. Agrochemical

50
Q

Saxitoxin & neosaxitoxin are examples of ( paralytic or diarrhetic ) shellfish poison ?

A

Paralytic shellfish poison

51
Q

Dinophysistoxin-1 is an example of (paralytic / diarrhetic ) shellfish poison?

A

Diarrhetic

52
Q

All of the following are synptoms of shellfish poisoning except?

Nausea
Vomiting
Anorexia
Diarrhea
Loss of long-term memory
Gastric bleeding
comma
Andominal cramps

A

Loss of long-term memory

53
Q

Which has the following function. (Saxitoxin - neosaxitoxin - tetrodoxin - dinophysistoxin -1)
Relaxing smooth muscle spasm

A

Tetrodoxin

54
Q

Fish livers as a source of vitamin x and x?

A & B
B &C
A & C
C & D
A & D
B & C

A

A & D

55
Q

Pyrethrum flower family?

A. Moraceae
B. Cannabinaceae
C. Compositae
D. Liliaceae

A

Compositae

56
Q

Pyrethrum flower

Chrys.. ciner..
Tan.. ciner..
Pyrethrum ciner

All are related to ( Compositae )

A

Also used as insecticide

57
Q

Pyrethrin percentage?

A. 35%
B. 15%
C. 25%
D. 45%

A

C. 25%

58
Q

Indian hemp family name?

A

Moraceae / cannabinaceae

59
Q

Enhance THC activity, antifungal, antibacterial, anti-inflammatory?

Cannabidiol or cannabichronene

A

Cannabichromene

60
Q

Cannabidiol is:

A. Antibacterial
B. Antifungal
C. Anti-imflammatory
D. Anticoagulant
E. Anticonvulsant

A

E. Anticonvulsant

61
Q

Cannabidiol is anticonvulsant, alongside it is?

A

Analgesic

62
Q

Delta-9 THC USED TO:?

A

Relief nausea and vomining caused by chemotherapy

63
Q

To stimulate the appetitie of aids patients, which country?

A. In the USA
B. In the UK
C In Asia

A

A. In the USA

64
Q

Dronabinol

A

In the UK

65
Q

Lophophora williamsii represents?
A. Podhyllium
B. Peyote
C catharanthus

A

B. Peyote

66
Q

Ingestion of peyotes results in
1- mydriasis
2. Bizarrencolour
3 flashing lights

Then becomes dim, drowsy

A
67
Q

Tumor inhibitor?

A. Ginseng
B. Podophyllum
C. Peyote

A

B. Podophyllum

68
Q

What parts of podophyllum are used for medicinal purpose?
A. Leaves and stems
B. Rhizome and roots
C. Barks
D. Flowers
E. Seeds

A

B. Rhizome and roots

69
Q

The main active component of Podophyllum?

A. Flavonoid
B. Terpene
C. Resin
D. Alkaloid

A

C. Resin

70
Q

American podophyllum yields?

A

2-8%

71
Q

Indian Podophyllum yields?

A

6-12%

72
Q

Desoxypodophyllotoxin, podophyllotoxone are ?
Cytotoxic? Yes or no?
Posses Antitumor activity ? Yes or no?

A

Yes

73
Q

Traditional use of podophyllum resin?

A. Treatment of lung cancer
B. Treatment of leukaemia
C. Treatment of watrs

A

C. Treatment of warts

74
Q

What compound is obtained from podophyllotoxin?

A

Etoposide

75
Q

A. Podophyllum hexandrum berberidaceae - Indian or american?

B. Podophyllum peltatum berberidaceae - Indian or american?

A

A. Indin

B. American

76
Q

Catharanthus roseus is a root or sub-shrub?

A

Sub-shrub

77
Q

Catharanthus.. Sub- shrub , belongs to family?

A

Apocynaceae

78
Q

How many alkaloids are found in catharanthus roseus?

A. 60
B. 100
C. 70
D. 150

A

D. 150

79
Q

The percentage of vincristine is?
L euro ( vincrostine)

Vinca uk (vinblastine)

A

0,0002%

80
Q

Hodgkin’s disease is treated by?

A. Vindesine
B. Viblastine
C. Vincristine
D. Vinoelbine

A

B. Vinblastine

81
Q

Lung, cervical, breast cancer are related to?

A. Vinblastine
B. Vindesine
C. Vincristine

A

C. Vincristine

82
Q

Vincristine has ( acute ) lymphatic leukemia. Which also has the same?

A

Vindesine

83
Q

S.N of plant associated with taxol?
A. Taxus brevifolia
B. Taxus canadensis
C. Taxus buccata
D. Taxus cuspidata

A

A. Taxus brevifolia

84
Q

Diterpenoid derivatives “ taxanes” are constituents of taxol (yes / no)?

A

Yes

85
Q

Taxotere can be used for ovarian cancer (true / false)?

A

False

Taxol —for ovarian cancer+ breast cancer

Taxotere — for breast cancer onnnnnly

86
Q

Pacl. Taxol
Doc. Taxotere

A

Paclitaxel (taxol)

Docetaxel (taxotere)

87
Q

Taxol isolated in ?

A. 1961
B. 1959
C. 1971
D. 1951

A

C. 1971

Phto (5 decks)

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