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pharm unit 5 > bisphosphonates > Flashcards

bisphosphonates Flashcards

1
Q

alendronate class

A

bisphosphonate

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2
Q

alendronate mechanism

A

reduces osteoclastic bone resorption

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3
Q

alendronate therapeutic

A

hypercalcemia, pagets, osteoporosis

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4
Q

alendronate side effects

A

esophageal irritation, iritis, myalgia AFF long term

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5
Q

risedronate class

A

bisphosphonate

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6
Q

risedronate mechanism

A

reduces osteoclastic activity

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7
Q

risedronate therapeutics

A

hypercalcemia, osteoporosis, pagets disease, reduces the fractures in OI

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8
Q

risedronate side effects

A

esophageal irritation, iritis, myalgia AFF long term

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9
Q

ibandronate class

A

bisphosphonate

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10
Q

ibandronate mechanism

A

reduces osteoclastic bone resorption

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11
Q

ibandronate therapeutics

A

hypercalcemia, reduces fractures in OI, osteoporosis.

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12
Q

ibandronate side effects

A

esophageal irritation, iritis, myalgia AFF long term

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13
Q

pamidronate class

A

bisphosphonate

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14
Q

pamidronate mechanism

A

reduces osteoclastic bone resorption

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15
Q

pamidronate therapeutics

A

hypercalcemia of malignancy, pagets, oseoporosis, fractures in OI

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16
Q

pamidronate SE

A

flu like symptoms, iritis, myalgia, AFF long term.

17
Q

zeladronic acid class

A

bisphos

18
Q

zeladronic acid mechanism

A

reduces osteoclastic bone resorpt

19
Q

zeladronic acid therapeutic

A

hypercalcemia of malignancy, pagets, OI.

20
Q

zeladronic acid SE

A

flu like, iritis, AFF long term. myalgia

21
Q

which bisphosphonates have to be given IV

A

pamidronate and zeladronic acid

22
Q

how long until the bisphosphonates take effect?

A

several days to see calcium lowered.

23
Q

what are the usual directions for taking bisphosphonates

A

sitting upright, water, fasting, no eating or drinking for 30 minutes.

pharm unit 5 (12 decks)

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