bisphosphonates Flashcards
alendronate class
bisphosphonate
alendronate mechanism
reduces osteoclastic bone resorption
alendronate therapeutic
hypercalcemia, pagets, osteoporosis
alendronate side effects
esophageal irritation, iritis, myalgia AFF long term
risedronate class
bisphosphonate
risedronate mechanism
reduces osteoclastic activity
risedronate therapeutics
hypercalcemia, osteoporosis, pagets disease, reduces the fractures in OI
risedronate side effects
esophageal irritation, iritis, myalgia AFF long term
ibandronate class
bisphosphonate
ibandronate mechanism
reduces osteoclastic bone resorption
ibandronate therapeutics
hypercalcemia, reduces fractures in OI, osteoporosis.
ibandronate side effects
esophageal irritation, iritis, myalgia AFF long term
pamidronate class
bisphosphonate
pamidronate mechanism
reduces osteoclastic bone resorption
pamidronate therapeutics
hypercalcemia of malignancy, pagets, oseoporosis, fractures in OI
pamidronate SE
flu like symptoms, iritis, myalgia, AFF long term.
zeladronic acid class
bisphos
zeladronic acid mechanism
reduces osteoclastic bone resorpt
zeladronic acid therapeutic
hypercalcemia of malignancy, pagets, OI.
zeladronic acid SE
flu like, iritis, AFF long term. myalgia
which bisphosphonates have to be given IV
pamidronate and zeladronic acid
how long until the bisphosphonates take effect?
several days to see calcium lowered.
what are the usual directions for taking bisphosphonates
sitting upright, water, fasting, no eating or drinking for 30 minutes.
