Birnaviridae Flashcards
1
Q
Describe family Birnaviridae.
A
-non enveloped virus, hexagonal in outline, single shell w icosahedral symmetry
-2 segments of linear double stranded RNA (A & B)
2
Q
Describe infectious bursal disease (IBD).
A
‘Gumboro disease’
-predilection for bursa of fabricius (cloacal bursa)
3
Q
Describe the pathogenesis of IBDV.
A
4
Q
Describe IBD clinical signs.
A
5
Q
Describe IBD vaccine.
A
-live IBD vacc made from fully or partially attenuated strains of virus = mild, intermediate, or intermediate plus (hot)
-mild vacc strains cause no bursal lesions cant be used effectively in chicks w maternal derived antibodies (MDA) until 4 wk of age as they are neutralized
