Bipolar disorder Flashcards
Bipolar disorder can present similarly to depressive disorder. True or false?
True
Definition
2 or more episodes in which the patient’s mood and activity levels are significantly disturbed.
This disturbance consisting on some occasions of hypomania/mania, and on others, depression
What is the difference between bipolar I and bipolar II ?
Bipolar I is more severe
- current/past full blown mania + current/past depression
Bipolar II - current/past hypomania + current/past depression
Bipolar I is more common than bipolar II. True or false?
False
Patient has NEVER met criteria for manic episode in bipolar II. True or false?
True
- only met criteria for hypomanic episode
A single episode of hypomania or mania is enough to diagnose bipolar disorder (even if the patient hasn’t been depressed yet). True or false?
True
The first episode of (hypo)mania on a background of depression has what significance?
The patient should be re-diagnosed with BIPOLAR DISORDER and not depression anymore
Classification of hypomanic episodes
Elevated/irritable mood to a degree that is definitely abnormal for the individual and this is sustained for at least 4 consecutive days.
A patient who is hypomanic will have psychotic symptoms. True or false?
False
Classification of hypomanic episodes - signs
At least 3 of the following should be present:
- increased activity or physical restlessness
- increased talkativeness
- difficulty in concentration or distractibility
- decreased need for sleep
- increased sexual energy
- mild spending sprees, or other types of reckless or irresponsible behaviour
Classification of manic episodes
Mood must be predominantly elevated, expansive or irritable, and definitely abnormal for the individual. The mood change must be prominent and sustained for at least 1 week.
Presence of psychotic symptoms
Classification of manic episodes - signs
At least 3 of the following signs:
- increased activity or physical restlessness
- V increased talkativeness (pressure of speech)
- Flight of ideas (racing thoughts)
- Loss of normal social inhibitions resulting in inappropriate behaviour
- decreased need for sleep
- inflated self esteem or grandiosity
- distractibility or constant changes in activity or plans
- reckless behaviour where the subject doesn’t recognise the risks
- marked sexual energy
Hypomania vs mania
Hypomania is clinically similar but not as severe as mania.
Manic episodes cause more impairment in function.
Manic episodes have psychotic symptoms.
Behaviour is more reckless in manic episodes.
Onset
Usually late teens - early 20s
Family history of bipolar disorder often results in earlier onset. true or false?
True
The amount of time people spend in euthymia (normal mood) is HIGH/LOW?
low
MSE - appearance
Wears bright clothes
Bright makeup
MSE - behaviour
Distractibility
Loss of normal social inhibitions / over-familiarity
eg swearing at drs appt
MSE - speech
Increased talkativeness
Pressured speech
Puns
MSE - thoughts
Increased flow - unable to keep track of what pt is talking about leaping between different convo topics Flight of ideas Grandiosity - pt thinks they are great Delusions
MSE - perception
Normal
or
Hallucinations
- only with MANIC episodes (not hypomanic episodes)
If the patient has hallucinations then what do they have?
Mania + psychotic symptoms
MSE - cognition
Loss of concentration
Mainly orientated
MSE - insight
Often no insight
Prognosis
Predictors of poor outcome in adolescents
Suicide risk
Acute treatment (manic episode)
Want to reduce mood in episodes of mania
- Anti-psychotics (oral)
- Benzodiazepines can be used for symptom control
Acute treatment (depressive episode)
Want to raise mood in episodes of depression
- Anti-depressants
ADs SHOULD NOT BE PRESCRIBED UNLESS THERE IS A MOOD STABILISER ALSO PRESCRIBED
Long term management
Mood stabilisers
What is the function of mood stabilisers?
To stabilise mood and prevent recurrence of both mania and depression
List 4 types of mood stabilisers
Lithium - gold standard
Anti-psychotics
Lamotrigine (if primarily depression)
Sodium valproate (if primarily manic/hypomanic)
It is not possible to give anti-depressants alone in bipolar disorder. What must they be combined with?
Mood stabiliser
Is psychological therapy useful in bipolar disorder?
Yes
- CBT
- Behavioural activation