Biosinteza proteinov Flashcards

1
Q

Zgradba ribosoma

A
  1. PROK: 50S+30S

2. EVK: 60S+40S

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2
Q

Kaj je funkcija velike in male podenote ribosoma?

A

Velika: kataliza nastanka peptidne vezi
Mala: dešifriranje zaporedja na mRNK

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3
Q

Kateri encimi vežejo AK na tRNK?

A

aminoacil-tRNK sintetaze

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4
Q

Kateri so STOP kodoni in kateri je START?

A
  1. UAA, UAG, UGA

2. AUG

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5
Q

Prednosti “wobble” baz?

A

Zmanjšane posledice mutacij, hitrejša disociacija tRNK in mRNK, dodatna fleksibilnost

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6
Q

Opiši peptidil transferazno aktivnost velike ribosomolne podenote.

A

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7
Q

Poraba energije pri translaciji.

A

4 visoko energijske molekule: 2 GTP v elongaciji, 1 ATP in 1 PP pri aktivaciji.

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8
Q

Toksin davice

A

Inaktivira eEF-2 s tem, da ADP-ribozilira AK diftamid, ki se nahaj v eEF-2.

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9
Q

Toksin ricina

A

Iz A in B podenote, A inaktivira encimsko aktivnost velike ribosomalne podenote tako, da inaktivira adenozin v podenoti 28S rRNK.

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