Biosimilars Generics

Question 1

Drugs and soceital wellbeing

Answer 1

Governnment (professional body) as a pharmacist
Which links to drug companies and patients

Question 2

Infant mortality and cheaper drugs

People living longer

Answer 2

This is due to the provision of cheaper drugs, thus available to everyone thus raising life expectancy.

Infant mortality has decreased, 120 per 1000 live births so 12%. The way people live, NHS, diet, living condition and better education.

Mothers since 100 years, out of every 1000 live births 1 in 25 chance of death for the mother.

Question 3

Biologics,generics and their small percentage.

Answer 3

From 2002 biologics have increased to 19-20%.
221 billion dollars of revenue.
These are not generics, they are biosimilars.
Generics are cheaper drugs available to more people.
Biosimilars are only a short percentage.

Question 4

Snake oil hoax

Answer 4

Chinese immigrants to america which brought snake oil over in the late 1800s
Supposidly cured Rheumatoid conditions
Situation then changed when the Food and Drug act was passed in 1906
This stipulated the chemical composition of approved medicines.

Question 5

Cuba/Russia/China

Answer 5

Have their own pharamceutical industry like cuba set up their own vaccine

Question 6

Small organic molecules

Answer 6

Many produced by fermentation proceses- antibiotics
Targeted at eukaryotic G protein coupled receptors and enzymes for acute and chronic conditions

The company has to file the patent for total synthesis

Question 7

Research drug companies

Answer 7

Find target, full synthesis of small mol
Pre-clinical studies
Fil patent for 20 years
Phase 1,2,3 studies
License granted for market and recoup investment
End of patent make money
There is already a market after the 20 years, thus the drugs can be sold for cheaper.

Governements set pharmacopeia standards:excipients, bioavailabilty and form