Biopsychology Flashcards
The central nervous system
The central nervous system
− Two main functions:
→ Control behaviour
→ Regulation of the body’s physiological processes
− Spinal cord:
→ Relay information between the brain and the rest of the body
→ Allows the brain to monitor + regulate bodily processes e.g. digestion
→ If damaged nerves below the damage point will be cut off from the brain + stop functioning
− Brain:
→ Cerebrum – largest part of the brain, split into 2 hemispheres + each hemisphere is split into 4 lobes, outer suface = cerebral cortex + is responsible for ‘higher order’ functions
→ Cerebellum – controls motor skills + balance, coordinating the muscle to allow precise movements
→ Diencephalon – consists of the thalamus + hypothalamus, thalamus receives nerve impulses from the senses sending them to the appropriate part of the brain to be processed, hypothalamus regulates body temp, hunger + thirst, link between the endocrine system + nervous system controlling the regular release of hormones
→ Brian stem – regulates automatic features e.g. breathing + heartbeat, motor + sensory neurons travel through allowing impulses to pass between the brain + the spinal cord
The peripheral nervous system
− Function = to relay nerve impulses from the CNS to the rest of the body + back again
− Somatic nervous stem:
→ Made up of pairs of cranial nerves + spinal nerves
→ Transmission of information to and from the CNS
→ Involves reflex actions
− Autonomic nervous system:
→ Regulates involuntary actions
→ Two branches that regulate the same organs but have the opposite effect on them
→ Sympathetic branch increases bodily activities
→ Parasympathetic branch maintains or decreases bodily activities
Structure of neurons
− Nucleus – serves to maintain the cell + keep the neuron functional
− Dendrites – receive messages from other cells + are covered with synaptic receptor cells
− Axon – the elongated fibre that extends from the cell body to the terminal endings + transmits the neural signal, the larger the axon the faster it transmits information
− Cell body/soma – where signals from the dendrites are joined and passed on, serves to maintain the cell and keep the neuron functional
− Terminal buttons – located at the end of the neuron + responsible for sending the signal to the other neurons
Neurons
− Neurons – cells that receive information + transmit it to other cells, essential part of the communication systems around the body
Sensory neuron
→ Tell the rest of the brain about the eternal + internal environment by processing information taken from the senses (sensory receptors)
→ Sensory receptors can be found in various parts of the body e.g. the ears, tongue + skin
→ Convert information from sensory receptors into neural impulse which are then translated into sensations (e.g. heat) when they reach the brain
→ Unipolar – only transmit messages from the body to the brain
Relay neuron
→ Carry messages from one part of the central nervous system to another
→ Connect motor + sensory neurons
→ Multipolar – both send + receive messages from many sources
→ Only exist in the brain + spinal cord (CNS)
Motor neuron
→ Carry signals from the CNS – helps organs, glands + muscles to function
→ Multipolar – have the capability of both sending and receiving messages
→ Motor neurons form synapses with muscles + control their contractions, when stimulated the motor neuron releases neurotransmitters that bind to receptors on the muscle + trigger a response in the form of muscle movement
→ Muscle relaxation is caused by the inhibition of the motor neuron
Excitatory neurotrasmitters
− the nervous systems ‘on-switches’ + increase the likelihood that an excitatory signal is sent to the postsynaptic cell which is more likely to fire, e.g. increased heart rate due to the activation of the muscle by noradrenaline
Inhibitory neurotransmitters
− the nervous systems ‘off-switches’ + decrease the likelihood that a neuron will fire, they are generally responsible for calming the mind + body by inducing e.g. sleep + filter out unnecessary excitatory signals, e.g. serotonin + GABA
The process of synoptic transmission
− Synaptic transmission is the process by which one neuron communicates with another. Information is passed down the axon of the neuron as an electrical impulse known as action potential.
− Once the action potential reaches the end of the axon it needs to be transferred to another neuron or tissue. It must cross over the synaptic gap between the presynaptic neuron and post-synaptic neuron.
− At the end of the neuron (in the axon terminal) are the synaptic vesicles, which contain chemical messengers, known as neurotransmitters.
− When the electrical impulse (action potential) reaches these synaptic vesicles, they release their contents of neurotransmitters.
− Neurotransmitters then carry the signal across the synaptic gap.
− They bind to receptor sites on the post-synaptic cell, thereby completing the process of synaptic transmission.
The endocrine system
− The endocrine system is composed of a series of glands which release chemicals known as hormones into the bloodstream + other bodily fluids
− Targets specific receptor cells on organs + regulates the activity of cells or organs within the body
− The endocrine system is controlled by the pituitary gland + hypothalamus + regulates by means of a ‘feedback loop’ to the hypothalamus
− Too much or too little activity of the endocrine system can lead to dysfunction
Pituitary gland
The pituitary gland is likely the most important gland in your body it is crucial to growth, mental development + reproduction, it influences + controls the rest of your endocrine system
Adrenal gland
The adrenal glands influence the way your body uses energy, they also release a hormone called adrenaline when you ae under stress + is essential for the fight or flight response
Pancreas
Releases the insulin your body need to metabolism sugar
Ovaries
Produce oestrogen + progesterone in women, also release egg cells
Testes
Are located in the scrotum, produce hormones called androgens + most importantly testosterone in men
The fight or flight response - The sympathomedullary pathway (SAM)
− Immediate (acute) stressors arouse the sympathetic branch of the autonomic nervous system
The hypothalamus detects stress —–
Activates the sympathetic branch of the autonomic nervous system (ANS) —–
Triggers the adrenal medulla —–
Releases adrenaline + nor-adrenaline
− Release of adrenaline results in quickening of heart rate + breathing, it also slows down digestion to conserve recourses for fight or flight
− The parasympathetic branch of the ANS returns heart rate + blood pressure to normal as well as speeding up digestion causing the body to relax
The fight or flight response - The hypothalamic pituitary-adrenal system (HPA)
− If stress continues (chronic) then the hypothalamic pituitary-adrenal system is increasingly activated
The hypothalamus detects stress + releases corticotrophin releasing factor (CRF/CRH) —–
The pituitary gland secrets adrenal-corticotropin hormone (ACTH) ——
Travels to the adrenal context —–
Releases corticosteroids (eg cortisol) into the blood stream
− Cortisol maintains a steady supply of blood sugar for continued energy which enables the body to cope with the stressor
− Cortisol release increases the ability to tolerate more pain BUT can impair cognitive ability + reduce immune system performance
Localisation of brain function
specific areas of the brain are associated with specific functions
Hemispheric lateralisation
− the divisions of functions bet. the two (asymmetrical) hemispheres, the brain is contralateral in most people (right hemisphere deals with the left hand side of the body + visa-versa) – e.g. what you see in your right visual field is processed by the left hemisphere
Left hemisphere
Contains the language centres (Broca’s + Wernicke’s areas)
Right hemisphere
− Recognising emotions
→ Heller + Levy – a photo of a face that has been split so that one half of the face is smiling + the other is neutral is shown, the motions displayed in the left side of the picture is the emotion recognised by the ppts, the right hemisphere is dominant for this task + it’s the left visual field which is processed by the right side of the brain
− Spatial relations
Fink + Halligan et. Al. – if you ask someone to identify the small detail in a picture there is greater activity in the left hemisphere, looking at the picture holistically (as a whole) prompts more activity in the right hemisphere, conclusion: the left hemisphere focuses on detail vs the right hemisphere which processes overall patterns
KEY STUDY: Phineas Gage (case study) - (localisation of the brain)
− Phineas worked on railways by placing dynamite into position + using a tamping iron (a metre-long rod with a diameter of 1 inch) to bed the dynamite in place using sand
− One day an accident occurred whereby the rod caused a spark + the dynamite blew up blasting the rod under his cheek bone through the back of his eye socket + out through the top of his forehead
− He recovered very well psychically + although he lost sight in his left eye there were no other apparent effects on his functioning
− However before the accident he was calm + well mannered, following the accident he exhibited unreliable hostile + rude behaviour, he used vulgar language which he never did prior to his injury
− This supports localisation as the damaged area had been responsible for functions e.g. palnning, reasoning + control
Motor cortex
− Located in the frontal lobe (both hemispheres)
− Responsible for complex movements e.g. writing, swimming, playing an instrument – NOT basic actions e.g. coughing or crying
− Works by sending messages (nerve impulses via the motor neurons) to the muscles via the brainstem + spinal cord
− It is the complexity of the movement in the area that dictates how many neurons are needed not the size of the body part
Somatosensory centres
− Somatosensory: sensations/touch
− Located in the parietal lobe of the brain along the postcentral gyrus (both hemispheres)
− The somatosensory cortex perceives touch, using sensory information from the skin it produces sensations of touch, pressure, pain + temperature
− More neuronal connections + therefore a larger amount of the somatosensory cortex are needed for touch sensitive areas of the body e.g. the face, particularly the lips
Visual centres (visual cortex)
− The brain has two visual cortices (one in each hemisphere) the visual cortex in the right hemisphere receives input from the left hand side of the visual field and visa-versa
− Its located in the occipital lobe at the back of the brain (both hemispheres)
− Light enters the eyes is received by the retina hitting the photoreceptors (rods + cones) at the back of the retina, nerve impulses then travel down the optic nerve to the brain where they are received by the thalamus, the thalamus acts as a relay station transmitting information to the visual cortex
− Within the main visual centre there is an area called Area V1 which seems to be necessary for visual perception, research has found that individuals with damage to this area report no vision of any kind: conscious vision, visual imagery while awake or in their dreams (Hurovitz et al)
− However some research has found that damage to Area V1 can lead to a condition known as ‘blindsight’ in which individuals report no vision so appear blind but are able to locate objects in a visual field by pointing at them – this suggests that some of the processing in the visual cortex is not conscious as they respond to visual stimuli that they do not consciously see therefore they may be two types of vision: one conscious + the other unconscious
− Overgaard et al.:
→ Conducted a case study about a 31 yr old women who experienced ‘blindsight’ following damage within her visual cortex which occurred as a result of brain haemorrhage
→ Researchers tested her with tests asking her to detect a letter shown on a screen she could not identify the letter but she did report awareness of something despite seeing nothing
→ This continued with many of the stimuli + when tested statistically there was found to be a sig relationship bet awareness of stimuli + accuracy
Auditory centres
− Located within the temporal lobes (both hemispheres) the information received from the right ear is processed mainly by the left hemisphere + visa-versa
− Concerned with hearing + processing sound information from both ears, information is transmitted about what the sound is + its location
− The auditory pathway begins in the cochlea in the inner ear where sound waves are converted to nerve impulses which travel via the auditory nerve to the auditory cortex in the brain
− On the journey to the cochlea to the brain nerve impulses passes through the brain stem+ thalamus:
→ In the brainstem information id processed through basic decoding i.e. duration + intensity of sound
→ In the thalamus further processing occurs of auditory stimulus + relay station
− If the primary auditory cortex in damaged it does not lead to total deafness, sounds can still be heard but if they require complex processing e.g. listening to music then this ability is compromised
− Research has found that the auditory cortex is not just involved with conscious sound it also processes auditory imagery, Meyer et al:
→ Found that when ppts watched silent films their primary auditory cortex in both hemispheres activated if a door is shut with force because they imagine a bang
→ The primary auditory cortex also processes auditory imagery
Broca’s area
− Located in the posterior portion of the frontal lobe of the left hemisphere (the left hemisphere is where the most language processing in the majority of the pop is situated)
− Responsible for speech production
− Broca’s aphasia (expressive aphasia): is the term used to describe patience’s with problems producing speech
− However individuals with Broca’s aphasia are not always unable to say all words e.g. Gardner + Zurif:
→ Found that nouns + verbs seem relatively unaffected in some patients with damage in Broca’s area but other classes of words e.g. prepositions + conjunctions cannot be spoken e.g. people with Broca’s aphasia can’t read out loud ‘to be or not to be’ but can say ‘two bee oar knot two bee’
KEY STUDY: Leborgne (case study) - (Broca’s area)
− Leborgne suffered with epilepsy throughout his childhood + eventually lost his ability to speak except for the word ‘Tan’
− When Broca conducted a post mortem of Leborgnes brain he found a lesion (area of damage – caused by his epilepsy) on the left frontal lobe
− As this was the only area of damage he concluded that it was the areas responsible for production of speech based on the deficit Leborgne exhibited
Wernicke’s area
− Located in the posterior portion of the left temporal lobe of the left hemisphere
− Involved in understanding language + accessing words
− Wernicke’s aphasia (receptive aphasia) is an impaired ability to understand language + and inability to extract meaning from spoken or written words
− Wernicke found that patients who had damage to this area close to the auditory cortex had specific language impairments whereby they could speak but were unable to understand language + displayed anomia (when someone struggles to find the word they need)
− Wernicke also noticed that people were able to speak fluently when they were able to access words quickly suggesting that damage to this area of the brain does not affect speech production
Interaction between the Broca’s and Wernicke’s areas (language centres)
− These two areas work together so we can understand + produce speech
− When someone speaks the sound travels through the ear + through the auditory cortex to the Wernicke’s area
− The motor region (located in the Broca’s area) is close to the area that controls the mouth, tongue + vocal cords
− The sensory region (located in the Wernicke’s area) is close to regions of the brain responsible for auditory + visual input
− Input from these regions is transferred to the Wernicke’s area where it is recognised as language + associated with meaning
− There is a neural loop (arcuate fasciculus) running bet. the Broca’s + Wernicke’s areas
Evaluation of localisation of function in the brain: The holistic theory of brain function argues that localisation of function is largely incorrect :(
P: The holistic theory of brain function argues that localisation of function is largely incorrect
E: Research conducted by Lashley on rats brains didn’t find any specific area included in memory, it appeared to be stored all over the brain – Lashley referred to this as the equipotentiality theory (the idea that basic motor + sensory functions are localised but higher mental functions e.g. cognitive memory were not
C: This casts doubt on the idea that specific areas perform specific functions however it may be difficult to extrapolate these findings to humans as there are psychological difference bet the two species
Evaluation of localisation of function in the brain: The fact that rehabilitation can help individuals to overcome brain trauma suggests that there is no localisation or lateralisation :(
P: The fact that rehabilitation can help individuals to overcome brain trauma suggests that there is no localisation or lateralisation
E: If there were task specific areas then there would be no brain plasticity, Lashley claimed that intact areas of the cortex could take over responsibility for specific cognitive function following damage to the area normally responsible for the function e.g. in the case of E.B. had his left hemisphere remove yet regained most of his language abilities
C: HOWEVER as he never fully recovered function then there is some localisation within certain areas of the brain
Evaluation of localisation of function in the brain: Research suggests that what might be more important is how brain areas communicate with each other rather than the idea that specific brain regions control a particular cognitive process/function :(
P: Research suggests that what might be more important is how brain areas communicate with each other rather than the idea that specific brain regions control a particular cognitive process/function
E: Wernicke claimed that although different regions of the brain had different specialist functions there are interdependent (in order to work they must interact with each other) e.g. complex behaviours like language, reading + movement are built up gradually as a stimulus enters the brain + moves through different structures before a response is produced
C: Therefore damage to the connection bet any two points in this process results in impairments that resemble damage to the localised brain region associated with a specific function
Evaluation of localisation of function in the brain: Language production may not be confined to Broca’s area alone. :(
P: Language production may not be confined to Broca’s area alone.
E: Dronkers et al. (2007) re-examined the preserved brain of Leborgne (Tan), using MRI brain imaging to reveal that other areas besides Broca’s area could have also contributed to the patients’ reduced speech abilities. Therefore, although lesions to Broca’s area alone can cause temporary speech disruption, they do not usually result in severe disruption of spoken language.
C: This suggests that language and cognition are far more complicated than once thought and involve networks of brain regions rather than being localised to specific areas
Evaluation of localisation of function in the brain: Individual differences :(
P: There are individual differences in language areas in that the pattern of activation observed in response to various language activities can vary from one person to the next.
E: For example, in a study of silent reading, Bavelier et al. (1997) found a large variability in individual patterns of activation across different individuals. Other studies have found significant gender differences in the size of the brain areas associated with language – Harasty et al. (1997) found that women have proportionally larger Broca’s and Wernicke’s areas than men.
C: This suggests that the size of these areas are related to the use of language i.e. there is generally a greater use of language amongst women.
Functional magnetic resonance imaging - fMRI (Ways of studying the brain)
− Measures changes in brain activity while a person performs a task
− Measures changes in blood flow in particular areas of the rain which indicates increased neural activity in those areas
− If an area of the brain becomes more active there is an increased demand for oxygen in that area – the brain responds to those extra demand by increasing blood flow by delivering oxygen in red blood cells
fMRI provides a moving picture of brain activity showing activity 1 sec after it occurs, it is also accurate to within 1-2mm in the brain
Strengths of fMRI :) (Ways of studying the brain)
− It is non-invasive nor does it expose the brain to potentially harmful radiation
− It offers objective + reliable measure of psychological processed than is possible with verbal reports
It provides a moving picture which means that patterns of activity can be compare rather than just the physiology of the brain (e.g. in a CAT scan)