Biomol/biocell: molécules type à connaître Flashcards

1
Q

UNG, UDG2

A

Retire les uraciles résultant de la désamination spontanée des cytosines de l’ADN

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2
Q

TDG

A

Impliquée dans les mésappariements T/G et U/G

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3
Q

MRN

A

Complexe reconnaissant une cassure double brin, à activité exonucléase + hélicase

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4
Q

RPA

A

Protéines équivalente à protéines SSB -> stabilise l’ADN simple brin

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5
Q

RAD51

A

Nucléofilament assemblé grâce à RAD52 et BRCA2

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6
Q

PARP1

A

Reconnaissance lésion –> BER

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7
Q

XPC/HR23B

A

Reconnaissance lésion –> NER

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8
Q

MSH2/MSH6

A

Reconnaissance lésion –> MMR

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9
Q

Ku 70-80

A

Reconnaissance lésion –> réparation par jonction d’extrémité non-homologues

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10
Q

OGG1

A

Retire les oxo-guanines résultant de l’oxydation des guanines de l’ADN

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